ugggh when i was a young'un golfer i couldnt understand how tiger woods could be sidelined from golf because of back injuries.
now......ack! just watching grass grow, huh? this sport hurts!
ugggh when i was a young'un golfer i couldnt understand how tiger woods could be sidelined from golf because of back injuries.
now......ack! just watching grass grow, huh? this sport hurts!
Gonna be a long road out of this one...............virus ain't going nowhere if people keep carrying on like this:
A cluster of coronavirus cases was reported in Arkansas after a swim party
Yakima in WA state is again holding rallies with hundreds of people not wearing masks or social distancing. They scream about their right to peacefully assemble and recalling Inslee. Their rights are being trampled on and it's wrong! wrong! wrong! Ignorant idiots. As I said earlier, Yakima has the highest per capita cases of CV19 on the entire west coast. While they were holding this little rally today (that was attended by state reps from across the state) they reported another 91 cases and 2 deaths today. Another rally will be held tomorrow. Honestly, they're like teenagers who think they know everything but really have no understanding of what they are spouting off about.
See that big circle down south? That's Yakima:
“When you see something that is not right, not just, not fair, you have a moral obligation to say something. To do something." Rep. John Lewis
Kindness is a bridge between all people
Dunkin’ Donuts Worker Dances With Customer Who Has Autism
Yup, Memorial weekend is gonna spike stuff bad.
“When you see something that is not right, not just, not fair, you have a moral obligation to say something. To do something." Rep. John Lewis
Kindness is a bridge between all people
Dunkin’ Donuts Worker Dances With Customer Who Has Autism
Hydroxychloroquine (HCQ) is an old drug, been around longer than most of us. Overall it's relatively safe, and has been used by loads of people for malaria prophylaxis and therapy over the years. I used it for almost a year while I was in malaria endemic areas, although more recent trips to such regions I'd used mefloquine as prophylaxis.
Arrhythmia (abnormal heart rhythm that can lead to sudden cardiac death) did not originally show up as a red flag (or "black box label") on initial HCQ studies, but that may be because it was approved so long ago (in the 50s). The prevalence is not determined, again because the drug was approved before there was extended clinical trial “vetting”, although there are case reports of it causing heart arrhythmias in the medical literature. I'm guessing the actual incidence is pretty low, prolly <5% more likely <1% or less.
HCQ has since been observed to be associated with significant heart arrhythmias in SARS CoV 2 patients receiving it in combination with azithromycin (AZR), another antibiotic which is in a class of antibiotics (known as macrolides) that have a track record of causing arrhythmias. Again, since AZR is a relatively old drug, (though much newer than HCQ, from the 80s) the incidence of cardiac side effects is not well established, although again probably on the low side as above.
The recent Lancet article that's in the news right now, confirms earlier recent reports, and showed that both HCQ and AZR were each independently associated with an increased risk of heart arrhythmia (roughly double) during hospitalization of SARS CoV 2 patients. Also, no clinical benefit was observed, actually lower survival noted, with an increased risk of in-hospital mortality. A weakness of this study is that it is a retrospective analysis (looking back) and less able to adequately control for outcomes. By that, I mean that there is a possibility that sicker patients were the ones that received the drugs, and therefore skewed the results. However, the authors do address this in their analysis, and did their best to control for such variables, so overall I think it’s pretty sound.
To answer Skidog's question, the best way I can describe it is that in general, we don't think malaria has direct cardiac effects, although it has indirect effects that may contribute to heart failure, and the association is not particularly strong. What little we know about SARS CoV 2 is that the virus itself may have more direct effects on the heart, in terms of inflammation-mediated microclotting events in the heart vessels that can lead to dysfunction. So the side effects of HCQ and AZR, individually and combined, may be more pronounced in SARS CoV2 patients than in malaria patients.
^^^ Thank you. You’ve combined a lot of points that I’ve been saying to people and articles I’ve quoted as reference.
Well maybe I'm the faggot America
I'm not a part of a redneck agenda
“When you see something that is not right, not just, not fair, you have a moral obligation to say something. To do something." Rep. John Lewis
Kindness is a bridge between all people
Dunkin’ Donuts Worker Dances With Customer Who Has Autism
Shit is getting real...wife's 96 year old uncle just diagnosed with the covid in Sarnia. Hoping for the best, preparing for the worst. He is in a retirement home and family hasn't been able to visit since March. If he dies, he will die alone, so take this shit seriously. This is our first family member directly affected, but my FIL is 92, but living at home (and we are doing everything we can to keep it that way.
For those of you who are happy to sacrifice a few old folks so we can go to bars, and the gun store without masks, fuck you!
I agree it is a constitutional right for Americans to be assholes...its just too bad that so many take the opportunity...iscariot
The bad guys get theirs sometimes.
The issue with the old folks homes, with patients that need a lot of hands on care, is that someone has to do those tasks. That job is stressful and depressing. How do you ask people to do that job without getting to have a life outside of work (also true for hospital staff). My girlfriend can't go visit her daughter, because she would have to be off work for 2 weeks after she got back and they're short staffed as is. The question is how long do people in that profession have to live this way?
If everyone had just hunkered down and done the right thing from the get-go, things would already be a lot better. NYT did an analysis in which they stated that had Trump told everyone to hunker down on March first, we would have had about 40,000 less deaths nationwide and this thing would almost be dicked.
Brazil's leader told his people to meet the virus like a man not a boy.
Jair Bolsonaro undermined Brazil’s coronavirus response. Now there’s a political crisis.
“When you see something that is not right, not just, not fair, you have a moral obligation to say something. To do something." Rep. John Lewis
Kindness is a bridge between all people
Dunkin’ Donuts Worker Dances With Customer Who Has Autism
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