Page 154 of 304 FirstFirst ... 149 150 151 152 153 154 155 156 157 158 159 ... LastLast
Results 3,826 to 3,850 of 7600
  1. #3826
    Join Date
    Jun 2009
    Location
    Matchbox 20
    Posts
    2,317
    A little story. True story. Relative. Vaccinated at 90 years old. Pfizer. Went to visit family for a bday. Granddaughter gave it to him fully 13 days after he got the shot. But he only got mildly sick. Pretty much completely over it in 3 days. Can't imagine what could have happened without the vaccine. Of course, they also would not have visited the BDay get together if it wasn't for the vaccine.
    Last edited by puregravity; 04-15-2021 at 05:53 PM. Reason: spelling
    OH, MY GAWD! ―John Hillerman  Big Billie Eilish fan.
    But that's a quibble to what PG posted (at first, anyway, I haven't read his latest book) ―jono
    we are not arguing about ski boots or fashionable clothing or spageheti O's which mean nothing in the grand scheme ― XXX-er

  2. #3827
    Join Date
    Jan 2004
    Location
    lakeside
    Posts
    805
    Quote Originally Posted by puregravity View Post
    A little story. True story. Relative. Vaccinated at 90 years old. Pfizer. Went to visit family for a bday. Granddaughter gave it to him fully 13 days after he got the shot. But he only gold mildly sick. Pretty much completely over it in 3 days. Can't imagine what could have happened without the vaccine. Of course, they also would not have visited the BDay get together if it wasn't for the vaccine.
    Holy shit!!!!!! Glad that ended that way and not anything worse.

  3. #3828
    Join Date
    Jan 2008
    Location
    truckee
    Posts
    17,578
    There's two issues with the idea of a booster--will the immunity of the original shot(s) wear off over time? The only way to know that is to follow antibody levels and also look for a surge in cases among the vaccinated with genotypes for which the vaccine is effective. And will people require a new vaccine for the variants--and the only way to tell that is to watch for cases in the vaccine with new genotypes. At this point they don't know what variant or variants to make a booster for, if it is needed. And of course a lot will depend on whether enough people get vaccinated to keep the generation of variants to a minimum, which seems unlikely. It's all speculative at this point.

    Apparently the US has 300M extra doses contracted for--presumably for boosters.

  4. #3829
    Join Date
    Nov 2003
    Location
    Portland
    Posts
    14,967
    Quote Originally Posted by bodywhomper View Post
    ... you mean: “while the anti-vaxxers gradually get the disease ‘naturally’ over and over again.”
    You're right. Thank you...although your correction makes me depressed. we're never getting out of this are we?
    Damn shame, throwing away a perfectly good white boy like that

  5. #3830
    Join Date
    Oct 2003
    Location
    9,300ft
    Posts
    18,939
    I suspect boosters will have a variety of mRNA sequences with variations to cover variants.

    Excited to see this applied to flu... they are working on this now...
    Quote Originally Posted by blurred
    skiing is hiking all day so that you can ski on shitty gear for 5 minutes.

  6. #3831
    Join Date
    Oct 2003
    Location
    Seattle
    Posts
    22,739
    Quote Originally Posted by Summit View Post
    I suspect boosters will have a variety of mRNA sequences with variations to cover variants.

    Excited to see this applied to flu... they are working on this now...
    I have a feeling what is learned from this is ultimately going to be transformative. The question is how long it will take to get there.

  7. #3832
    Join Date
    Dec 2004
    Location
    Where the sheets have no stains
    Posts
    16,454
    Quote Originally Posted by Adolf Allerbush View Post
    You're right. Thank you...although your correction makes me depressed. we're never getting out of this are we?
    Probably not, we have normalized it and as long as only around 60% of the population is immunized there will be enough variant going around that we will have the learn to live with it.
    I have been in this State for 30 years and I am willing to admit that I am part of the problem.

  8. #3833
    Join Date
    Nov 2002
    Location
    EWA
    Posts
    19,843
    41k out of 60k vaccinated in W2 county.

    Today's clinic was a sell out with many young people coming in for the jab now that it's 16+. People were actually whooping and a hollering when the doors opened. It was like we were letting then into a concert. LOL!
    When you see something that is not right, not just, not fair, you have a moral obligation to say something. To do something." Rep. John Lewis


    Kindness is a bridge between all people

    Dunkin’ Donuts Worker Dances With Customer Who Has Autism

  9. #3834
    Join Date
    Nov 2005
    Location
    Down In A Hole, Up in the Sky
    Posts
    30,431
    Read on another forum:

    “ Friend of mine runs an au pair program in the area. She is having problems with a host family freaking out about their au pair getting vaccinated. They are afraid that if the au pair gets a shot she will give the family blood clots. They have absolutely no concerns of actually contracting COVID.”
    Forum Cross Pollinator

  10. #3835
    Join Date
    Mar 2008
    Location
    the ham
    Posts
    9,828
    Not sure I believe that's for real, but...

    Blood clots are contagious now? It should hurt to be that fucking stupid. Goddamned idiocracy.

  11. #3836
    Join Date
    Oct 2012
    Posts
    10,286
    Quote Originally Posted by Adolf Allerbush View Post
    You're right. Thank you...although your correction makes me depressed. we're never getting out of this are we?
    We weren't getting out of this without closing borders regardless of the vaccine(s).

    There's 8 billion people on this Earth and the bats or lab or whatever released a species jumping rapidly mutating chimera.

    Your best option is to get the shots and get and stay healthy https://bjsm.bmj.com/content/bjsport...04080.full.pdf

  12. #3837
    Join Date
    Oct 2003
    Location
    Seattle
    Posts
    22,739
    Quote Originally Posted by rideit View Post
    Read on another forum:

    “ Friend of mine runs an au pair program in the area. She is having problems with a host family freaking out about their au pair getting vaccinated. They are afraid that if the au pair gets a shot she will give the family blood clots. They have absolutely no concerns of actually contracting COVID.”
    Well, I guess they can afford the au pair since there's no chance their kids will ever go to college.

  13. #3838
    Join Date
    Jan 2008
    Location
    truckee
    Posts
    17,578
    Quote Originally Posted by The AD View Post
    Well, I guess they can afford the au pair since there's no chance their kids will ever go to college.
    If they can afford an au pair there is a college that will take the kids no matter how stupid they are. If all those Kennedy's went to Harvard . . .

  14. #3839
    Join Date
    Apr 2004
    Location
    Southeast New York
    Posts
    8,574
    Quote Originally Posted by KQ View Post
    This site's raison d'être is women's plumbing.
    Ha! Nailed it.

  15. #3840
    Join Date
    Oct 2003
    Location
    closer
    Posts
    3,604
    btw. could we all say "i got the Biontech vax?" Pfizer only distributes it (and makes shitloads of money with it) worldwide.
    It's a war of the mind and we're armed to the teeth.

  16. #3841
    Join Date
    Jan 2007
    Location
    Upstate
    Posts
    7,496
    Quote Originally Posted by old goat View Post
    There's two issues with the idea of a booster--will the immunity of the original shot(s) wear off over time? The only way to know that is to follow antibody levels and also look for a surge in cases among the vaccinated with genotypes for which the vaccine is effective. And will people require a new vaccine for the variants--and the only way to tell that is to watch for cases in the vaccine with new genotypes. At this point they don't know what variant or variants to make a booster for, if it is needed. And of course a lot will depend on whether enough people get vaccinated to keep the generation of variants to a minimum, which seems unlikely. It's all speculative at this point.
    This is the paper everyone is quoting when it comes to duration of protection from natural infection.
    https://science.sciencemag.org/conte...f4063.full.pdf

    "... simple serological tests for SARS-CoV-2 antibodies do not reflect the richness and durability of immune memory to SARS-CoV-2"

    Shouldn't be surprising to anyone that it's more complicated than just antibodies.

    Name:  Screen Shot 2021-04-16 at 9.03.55 AM.png
Views: 390
Size:  220.2 KB

  17. #3842
    Join Date
    Oct 2004
    Location
    50 miles E of Paradise
    Posts
    11,289
    ^^^Can someone explain this (beyond “it’s complicated”) in terms a liberal arts major can understand?
    Check Out Ullr's Mobile Avalanche Safety Tools for iOS and Android
    www.ullrlabs.com

  18. #3843
    Join Date
    Jan 2006
    Location
    Alpental
    Posts
    6,108
    Quote Originally Posted by TBS View Post
    ^^^Can someone explain this (beyond “it’s complicated”) in terms a liberal arts major can understand?
    Color coded for tracking 5 immune parameters over time, 5 = all 5 present, red 4 (no cd8), orange 4 (no b cell at 1 mos), blue 4 (no cd4), grey (no IgG). Everyone maintained either IgG or IgA antibody, increased B cells that make the antibodies, some declines in specific parameters for CD8 and CD4 T cell subsets.

    Immune memory isn't going to wain at 1 yr, it is durable based on the body of info about sars1 and sars2.
    Neutralizing Ab in circulation or from memory b cells remains the only mechanism to prevent infection, t cell components kick in day 3-5 and help limit severity of disease but the massive (1000-fold) heterogeneity in the immune response means some % remain susceptible to reinfection and disease.

    T cell responses should persist across the Variants of Concern, but continued mutation at binding sites for neutralizing antibodies reduce their effectiveness at limiting infection ( so possiblyallow transmission too). The UK strain is now dominant in the USA and accounts for 40% of cases.
    Move upside and let the man go through...

  19. #3844
    Join Date
    Jan 2008
    Location
    truckee
    Posts
    17,578
    Quote Originally Posted by TBS View Post
    ^^^Can someone explain this (beyond “it’s complicated”) in terms a liberal arts major can understand?
    No. But I'll try. There are multiple factors in immunity. Serum antibodies, which are easily measured with a blood test are only one of them. Therefore, you cannot tell someone is no longer immune by measuring their antibody levels. And think about it--it would be inefficient for the body to maintain high antibody levels for every disease you've ever been exposed to. What the body maintains is the ability to rapidly produce antibodies when re-exposed.
    So at 6 months people retained multiple immune capabilities.
    I would add that vaccination produces a stronger immune response than natural infection.

    This is why we need better STEM education. :-)

  20. #3845
    Join Date
    Nov 2002
    Location
    EWA
    Posts
    19,843
    Quote Originally Posted by old goat View Post

    This is why we need better education. :-)
    FIFY
    When you see something that is not right, not just, not fair, you have a moral obligation to say something. To do something." Rep. John Lewis


    Kindness is a bridge between all people

    Dunkin’ Donuts Worker Dances With Customer Who Has Autism

  21. #3846
    Join Date
    May 2002
    Posts
    33,372

  22. #3847
    Join Date
    Sep 2006
    Posts
    5,609
    Quote Originally Posted by Bunion 2020 View Post
    Probably not, we have normalized it and as long as only around 60% of the population is immunized there will be enough variant going around that we will have the learn to live with it.
    The nurse who jabbed me with shot #1 basically said this was the scenario we would be dealing with. Kind of like the flu with variants in different locations and need for different vaccine formulas to deal with the variants.
    "We don't beat the reaper by living longer, we beat the reaper by living well and living fully." - Randy Pausch

  23. #3848
    Join Date
    Oct 2003
    Location
    Aspen
    Posts
    8,502
    Quote Originally Posted by Toadman View Post
    The nurse who jabbed me with shot #1 basically said this was the scenario we would be dealing with. Kind of like the flu with variants in different locations and need for different vaccine formulas to deal with the variants.
    Hopefully that universal coronavirus vaccine they're working on pans out.

  24. #3849
    Join Date
    Nov 2012
    Location
    GNARvada
    Posts
    3,715
    Moderna #2 in the arm - how long is the erection supposed to last?

  25. #3850
    Join Date
    Apr 2006
    Location
    Spokane/Schweitzer
    Posts
    6,406
    If more than 4 hours....well....you know the drill

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •