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  1. #19876
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    Maybe I missed it upthread, has there been data/ analysis remicron between 2x and 3x vax? And hospitalization rates comparing 2x and 3x vaxed for omicron?

  2. #19877
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    More is better. You're welcome.
    A few people feel the rain. Most people just get wet.

  3. #19878
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    Iím just trying to make sense of the city of San Joseís new mandate. Hereís a press release q&a: https://www.google.com/amp/s/www.mer...t-mandate/amp/

  4. #19879
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    To Vaccinate or Not---The Rat Flu Odyssey Continues

    It finally got me.

    Girlfriend and two sons had it the last two weeks. I saw her Friday night and the Sunday before last. Only saw her Friday because it was my 50th. I tested negative 2x last week.

    it either incubated 7 days, or less than 2.

    So far just a light cough, felt like shit Sunday night. Slightly better already. Triple vaxed.

    She developed symptoms a week after her boys did.


    Sent from my iPhone using TGR Forums

  5. #19880
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    My illness was similar. Happy to be vaxed.
    A few people feel the rain. Most people just get wet.

  6. #19881
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    Quote Originally Posted by Cono Este View Post
    It finally got me.

    Girlfriend and two sons had it the last two weeks. I saw her Friday night and the Sunday before last. Only saw her Friday because it was my 50th. I tested negative 2x last week.

    it either incubated 7 days, or less than 2.

    So far just a light cough, felt like shit Sunday night. Slightly better already. Triple vaxed.

    She developed symptoms a week after her boys did.


    Sent from my iPhone using TGR Forums
    Grow up and stop celebrating your birthday


    Sent from my iPhone using TGR Forums

  7. #19882
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    Quote Originally Posted by bodywhomper View Post
    Maybe I missed it upthread, has there been data/ analysis remicron between 2x and 3x vax? And hospitalization rates comparing 2x and 3x vaxed for omicron?
    I haven't seen anything as strong as the studies on booster effectiveness against delta that Summit posted a while back (showing stronger results for boosted against delta than unboosted against original), but this does look pretty compelling (figure 2 is a quick synopsis--note the J&J crossovers to mRNA doing much better than the one who got 2xJ&J):

    https://pubmed.ncbi.nlm.nih.gov/34995482/

    "we measured the neutralization potency of sera from 88 mRNA-1273, 111 BNT162b, and 40 Ad26.COV2.S vaccine recipients against wild-type, Delta, and Omicron SARS-CoV-2 pseudoviruses. We included individuals that received their primary series recently (<3 months), distantly (6-12 months), or an additional "booster" dose, while accounting for prior SARS-CoV-2 infection. Remarkably, neutralization of Omicron was undetectable in most vaccinees. However, individuals boosted with mRNA vaccines exhibited potent neutralization of Omicron, only 4-6-fold lower than wild type, suggesting enhanced cross-reactivity of neutralizing antibody responses. In addition, we find that Omicron pseudovirus infects more efficiently than other variants tested. Overall, this study highlights the importance of additional mRNA doses to broaden neutralizing antibody responses against highly divergent SARS-CoV-2 variants."

  8. #19883
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    Quote Originally Posted by wooley12 View Post
    More is better. You're welcome.
    https://www.cnn.com/2022/01/17/healt...ata/index.html

    Science disagrees with you, but OK.

  9. #19884
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    Quote Originally Posted by jono View Post
    I haven't seen anything as strong as the studies on booster effectiveness against delta that Summit posted a while back (showing stronger results for boosted against delta than unboosted against original), but this does look pretty compelling (figure 2 is a quick synopsis--note the J&J crossovers to mRNA doing much better than the one who got 2xJ&J):

    https://pubmed.ncbi.nlm.nih.gov/34995482/

    "we measured the neutralization potency of sera from 88 mRNA-1273, 111 BNT162b, and 40 Ad26.COV2.S vaccine recipients against wild-type, Delta, and Omicron SARS-CoV-2 pseudoviruses. We included individuals that received their primary series recently (<3 months), distantly (6-12 months), or an additional "booster" dose, while accounting for prior SARS-CoV-2 infection. Remarkably, neutralization of Omicron was undetectable in most vaccinees. However, individuals boosted with mRNA vaccines exhibited potent neutralization of Omicron, only 4-6-fold lower than wild type, suggesting enhanced cross-reactivity of neutralizing antibody responses. In addition, we find that Omicron pseudovirus infects more efficiently than other variants tested. Overall, this study highlights the importance of additional mRNA doses to broaden neutralizing antibody responses against highly divergent SARS-CoV-2 variants."
    Name:  gr2_lrg.jpg
Views: 285
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    Figure 2 from the abstract cited above - I believe this is important information and shows the importance of boosters -

    the right column of Chart C shows the benefit of the booster - I have been seeing numbers that show antibody response with the booster is 37% to 54% better than an initial vaccination series alone ;

    to those who figure omicron is 'not that bad' and are just going to take your chances with omicron,
    Please remember delta is still out there, And omicron is putting people in the hospital.


    Thank you for the link, jono --

    tj
    Last edited by skiJ; 01-18-2022 at 09:44 AM.

  10. #19885
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    Quote Originally Posted by Asspen View Post
    https://www.cnn.com/2022/01/17/healt...ata/index.html

    Science disagrees with you, but OK.
    asspan lieing with covid misinformation, whatís new?
    We have a follow-up of the Pfizer vaccine for two weeks now, and we have a follow-up of the Moderna vaccine just for one week at this time point. And what we see is that the Pfizer vaccine, after two weeks, you see an enhancement or increase in the number of antibodies and neutralizing antibodies -- a pretty nice increase. It's even a little bit higher than what we had after the third dose," Regev-Yochay said. "Yet, this is probably not enough for the Omicron."

  11. #19886
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    Quote Originally Posted by dunfree View Post
    asspan lieing with covid misinformation, whatís new?
    Worth calling out the article context was 'preventing infection'. No reference on outcomes (death/hospitalization).

  12. #19887
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    Quote Originally Posted by dunfree View Post
    asspan lieing with covid misinformation, what’s new?
    1. I'm referencing a CNN article, that's the gold standard of "trusted" of a "news source" as you authoritarians prefer.

    2. In YOUR quote: ""Yet, this is probably not enough for the Omicron."

    Bill Gates came out and addressed a few points about the limitations of our current vaccines:

    "The vaccines we have prevent severe disease and death very well but they are missing two key things.

    First they still allow infections ("breakthrough") and the duration appears to be limited.

    We need vaccines that prevent re-infection and have many years of duration.#" -Bill Gates


    Like I said on page 200 of this debate: When does the vaccine version 2.0 come out? Version 1.0 doesn't seem up to the task anymore.

  13. #19888
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    Quote Originally Posted by Asspen View Post
    1. I'm referencing a CNN article, that's about as "trusted" of a "news source" as you authoritarians prefer.

    2. In YOUR quote: ""Yet, this is probably not enough for the Omicron."

    Bill Gates came out and addressed a few points about the limitations of our current vaccines:

    "The vaccines we have prevent severe disease and death very well but they are missing two key things.

    First they still allow infections ("breakthrough") and the duration appears to be limited.

    We need vaccines that prevent re-infection and have many years of duration.#" -Bill Gates


    Like I said on page 200 of this debate: When does the vaccine version 2.0 come out? Version 1.0 doesn't seem up to the task anymore.
    You and Bill will continue to be disappointed in all likelihood. Here's a document you may find useful in understanding how vaccines work: https://www.who.int/ith/chapters/ith...chap6.pdf?ua=1

    Vaccination and other precautions
    Despite their success in preventing disease, vaccines rarely protect 100% of the
    recipients. The traveller should not assume that there is no risk of contracting the
    disease(s) against which he/she has been vaccinated. For example, immunization is not a
    substitute for avoiding potentially contaminated food and water. Therefore, all additional
    precautions against infection should be carefully considered (Chapter 3).
    One of the infectious disease experts on here (i.e., not you or me) can clarify this more if you need I'm sure. My understanding is that there aren't that many vaccines that provide sterilizing immunity which is what you are wanting...to be honest, we all want that right? It's just not very likely.

    Another article you might find useful: https://www.theatlantic.com/science/...ccines/620023/

    COVID-19 vaccines were never going to give us sterilizing immunity; itís possible they never will. But the reason isnít just their design, or the wily nature of the virus, or heavy and frequent exposures, though those factors all play a role. Itís that sterilizing immunity itself might be a biological myth.
    Damn shame, throwing away a perfectly good white boy like that

  14. #19889
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    If you guys put Asspen on ignore he can fuck that chicken all by himself and not pollute this thread with a constant stream of bullshit.

    Please? Do it for the children...

  15. #19890
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    Good advice. That guy has a bee in his bonnet so I mercifully have him on ignore.
    A few people feel the rain. Most people just get wet.

  16. #19891
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    Quote Originally Posted by Adolf Allerbush View Post
    You and Bill will continue to be disappointed in all likelihood. Here's a document you may find useful in understanding how vaccines work: https://www.who.int/ith/chapters/ith...chap6.pdf?ua=1



    One of the infectious disease experts on here (i.e., not you or me) can clarify this more if you need I'm sure. My understanding is that there aren't that many vaccines that provide sterilizing immunity which is what you are wanting...to be honest, we all want that right? It's just not very likely.

    Another article you might find useful: https://www.theatlantic.com/science/...ccines/620023/
    We get it. It's like the flu vaccine. It doesn't prevent infection or transmission, but helps the individual experience milder symptoms and not require hospital care.

    My and Bill Gates concern at this point is the poor DURATION of our current vaccines.

  17. #19892
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    Quote Originally Posted by wooley12 View Post
    Good advice. That guy has a bee in his bonnet so I mercifully have him on ignore.
    Stay in your echo chamber.

    Your opinions were formed in an era when black people weren't allowed to patronize the same businesses as you. Times have changed. You can't buy a house and support a family as a one income factory worker anymore.

    Your generation fucked up society, the environment, and the world for the rest of us.

    Boomers will be looked on in history as the ME FIRST generation that lived through the easiest of times in American history, and all they did was consume consume consume and took out loans to be paid by their grandchildren with interest.

  18. #19893
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    Quote Originally Posted by Asspen View Post
    We get it. It's like the flu vaccine. It doesn't prevent infection or transmission, but helps the individual experience milder symptoms and not require hospital care.

    My and Bill Gates concern at this point is the poor DURATION of our current vaccines.
    There's nothing factual about the bold. If you don't understand why, then I suggest you consult an expert.

  19. #19894
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    Quote Originally Posted by huckbucket View Post
    There's nothing factual about the bold. If you don't understand why, then I suggest you consult an expert.
    Please, good sir... use the Ignore function. Do it for the children...


  20. #19895
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    Quote Originally Posted by Adolf Allerbush View Post
    You and Bill will continue to be disappointed in all likelihood. Here's a document you may find useful in understanding how vaccines work: https://www.who.int/ith/chapters/ith...chap6.pdf?ua=1



    One of the infectious disease experts on here (i.e., not you or me) can clarify this more if you need I'm sure. My understanding is that there aren't that many vaccines that provide sterilizing immunity which is what you are wanting...to be honest, we all want that right? It's just not very likely.

    Another article you might find useful: https://www.theatlantic.com/science/...ccines/620023/
    Wiping out a disease with a vaccine has only been accomplished once--smallpox. The world is close on polio but may never get there. All the other diseases we vaccinate for are still endemic, still infect unvaccinated and immunocompromised people, and require continued vaccination of children. The success in keeping the cases of an infectious disease to a minimum depend on how good the vaccine is and how many people are vaccinated.

    As far as how good the vaccine is--a lot depends on how the virus continues to mutate. It is very likely that a better vaccine against omicron can be made fairly quickly, but whether this is a wise idea depends on whether omicron establishes itself as the or one of the persistent strains for longer than a few months. Given the frequency of breakthrough cases it seems to that if omicron is the strain we have to defend against in the long run, omicron vaccines will be needed.

    Even if the vaccination is not completely protective your chances of getting the disease is very low if you are rarely exposed to it. That is the hope with Covid--that we can somehow manage to vaccinate enough people to make exposure rare.

    It may turn out that covid is more like flu--continually mutating so that frequent revaccination is necessary, which would preclude vaccinating more than a fraction of the population. But it is way to soon to accept this. For now the biggest obstacle to controlling the virus as we have controlled diseases like measles and chickenpox is not scientific but the pigheadedness of the populace.

  21. #19896
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    Quote Originally Posted by huckbucket View Post
    There's nothing factual about the bold. If you don't understand why, then I suggest you consult an expert.
    Was the bucket on your head all last month? Omicron has changed the game.

  22. #19897
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    Quote Originally Posted by skiJ View Post
    Name:  gr2_lrg.jpg
Views: 285
Size:  180.5 KB

    to those who figure omicron is 'not that bad' and are just going to take your chances with omicron,
    Please remember delta is still out there, And omicron is putting people in the hospital.
    The current CDC estimate is that Delta is now .5% of all cases.

  23. #19898
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    So you agree. It's still here. Good
    A few people feel the rain. Most people just get wet.

  24. #19899
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    Quote Originally Posted by bodywhomper View Post
    Maybe I missed it upthread, has there been data/ analysis remicron between 2x and 3x vax? And hospitalization rates comparing 2x and 3x vaxed for omicron?
    https://twitter.com/EricTopol/status...26194623086596

    Latest data from @UKHSA for Omicron vaccine effectiveness vs hospitalization
    Booster provides very high protection thru 10+ weeks
    Without it, VE down to 44% by >6 months

  25. #19900
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    perhaps all we can do is repeatedly refute some of these claims -
    The vaccine IS doing what it was designed to do ;
    vaccination limits disease, and vaccination also reduces the spread of the disease, by limiting transmission by Vaccinated.

    critics claim otherwise, and omicron certainly encourages the criticism ;

    it is good that Mr. Gates has the means to promote vaccine technology
    ( I trust if the comments quoted above are genuine, funding for vaccine technology research is being provided ) ;


    I reject the claims that vaccination is only of benefit to the individual -
    I believe the models that project without vaccination, the USofA would likely have more than three million dead.
    beyond the conflict that some people prefer, I do not understand the benefit to those who claim Not to be anti-vaccination, but use their energy to promote the anti-vaccination platform
    ...


    oh. it's not like the flu vaccine.
    If in 100 years it is like Influenza ,,, That will be disappointing .

    Please get your booster
    ( delta is still out there, and don't kid yourself - omicron can be fatal. )

    Please get your booster --

    Thank you. tj

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