Results 5,601 to 5,625 of 23206
-
05-19-2021, 10:20 AM #5601
-
05-19-2021, 10:22 AM #5602
-
05-19-2021, 10:32 AM #5603
My arm was pretty sore after Pfizer #2 but I went golfing the next day and that helped immensely.
-
05-19-2021, 10:35 AM #5604
Some more info on the Yankees' cases and some other interesting ideas on PCRs vs antigen tests.
https://nymag.com/intelligencer/2021...-outbreak.html
-
05-19-2021, 10:36 AM #5605
EU travel is about to open up to those with vaccinations! Already booked a trip to Italy next year. Maybe go back to Germany this year? Flash that card to go? Come on Canada...we aren't all idiots here, let us back in! Lol
-
05-19-2021, 10:36 AM #5606
-
05-19-2021, 10:41 AM #5607
-
05-19-2021, 10:52 AM #5608
-
05-19-2021, 10:59 AM #5609
-
05-19-2021, 11:05 AM #5610"fuck off you asshat gaper shit for brains fucktard wanker." - Jesus Christ
"She was tossing her bean salad with the vigor of a Drunken Pop princess so I walked out of the corner and said.... "need a hand?"" - Odin
"everybody's got their hooks into you, fuck em....forge on motherfuckers, drag all those bitches across the goal line with you." - (not so) ill-advised strategy
-
05-19-2021, 11:07 AM #5611
-
05-19-2021, 11:10 AM #5612
-
05-19-2021, 11:27 AM #5613
-
05-19-2021, 11:43 AM #5614one of those sickos
- Join Date
- Oct 2005
- Location
- Tahoe-ish
- Posts
- 3,139
I haven't unfollowed this particular idiot on FB because he periodically brings the gold. His friends, apparently, are also morons.
ride bikes, climb, ski, travel, cook, work to fund former, repeat.
-
05-19-2021, 11:58 AM #5615
-
05-19-2021, 12:02 PM #5616
-
05-19-2021, 12:55 PM #5617
-
05-19-2021, 01:03 PM #5618
-
05-19-2021, 11:38 PM #5619Registered User
- Join Date
- May 2016
- Posts
- 3,580
I know it’s been a few days, but I did want to acknowledge that you’re correct, “effective” relates to weather you get symptomatic illness. But that makes it at least as likely to get caught in a PCR test. If they had used one of the mRNA vaccines, it would have much less likely caught by the test.
J &J made the choice of being the cheap, convenient vaccine for the masses. There were studies that showed increased “effectiveness” with a 2 shot regimen compared to a single shot, but they went with single shot for the reasons stated above.
But, not a problem, the J&J vax is pretty good at reducing serious illness and deaths. Just don’t expect it to do well in a highly tested environment.
-
05-20-2021, 08:20 AM #5620
J&J is more effective at preventing severe/critical illness >4 weeks after inoculation vs 2. If you get into the data, J&J is quite a bit more effective 6-8 weeks after inoculation where it is competitive with mRNA vaccine efficacy... (of course mRNA efficacy data is was measured 5-6 weeks after the first dose).
But for whatever reason (simplicity? realism?) they've chose "2 weeks after you last dose" as the metric for "fully vaccinated."Originally Posted by blurred
-
05-20-2021, 08:48 AM #5621
Huh. That's interesting. The long term data on this stuff is going to be fascinating to track. What if it ends up that the J&J (more like a "traditional" vaccine, right?) ends up trending up for long term efficacy, and the mRNA vaccines end up trending down over the long term, and they end up crossing paths with the J&J being most effective and the Moderna/Pfizer shots being worthless after a period of time without boosters. Only time will tell I suppose. Will be interesting to see what's up in year 0 + 1, 2, 3...
-
05-20-2021, 09:15 AM #5622
No, I wouldn't call J&J more like a "traditional" vaccine. It's a viral vector vaccine. It uses a modified virus to deliver DNA to a cell where it then generates mRNA that creates the spike protein for the immune system to target. The Pfizer and Moderna vaccines use a lipid particle to deliver mRNA to generate spike protein for the immune system to train against. Given that information, it seems unlikely that Pfizer/Moderna efficacy would decrease over the long term vs J&J. I was mostly speaking to the oft quoted "66%" J&J efficacy seeming much lower in comparison to mRNA because the timeframes of comparison were much different (there are also differences in time, variant prevalence, and case severity groupings that make the efficacy from Phase III harder to compare).
"Traditional" vaccine are more like those that use attenuated or inactivated virus, like the ChiCom company Sinovac's CoronaVac vaccine that has really crappy efficacy (<50%). For this type of vaccine you have to make the virus inactive (so that you don't get the disease) without also destroying immune targets you want to train against (the spike proteins on the virus). You also have to make sure you don't have the problems you get with with real infection such as harmful immune reactions or training the immune system against the wrong targets. The "traditional" inactivated vaccine is "dirtier" in that you are placing a lot more wildcards into the whole process.Originally Posted by blurred
-
05-20-2021, 09:16 AM #5623______
- Join Date
- Aug 2020
- Posts
- 1,218
My arm has hurt in a similar way with every vaccination I have received as an adult, particularly my tetanus booster.
This wasn’t any worse.
Moving it often helped a lot. Swimming motion, in and out, up and down, etc
-
05-20-2021, 09:40 AM #5624
To make a simpler compairson for MF: it's two different wrappings for presents. The J&J is a gift wrapped in a box with wrapping paper and the Pfizer/Moderna is just a gift bag with some tissue paper. Both contain the same present as far as your body is concerned, but the delivery method and unwrapping is different.
The efficacy differences are not worth comparing one to the next. The tests were performed on different people, in different countries which had different amounts of different variants floating around. The J&J trials faced the most kinds of variants while Pfizer/Moderna didn't. You can't compare their efficacy percentages because they didn't take the same test. It's like saying Pfizer got 95% on their math test and J&J got 66% on the Princeton entrance exam. They're not comparable scores.Wait, how can we trust this guy^^^ He's clearly not DJSapp
-
05-20-2021, 09:45 AM #5625
Bookmarks