Fear and Loathing, a Rat Flu Odyssey

**pureantigravity** · 01-06-2021, 08:27 PM

Originally Posted by old goat

mRNA vaccines are used in veterinary medicine, so there is that. The basic immune and protein synthetic mechanisms are the same as in humans.
is it possible that tinkering with the protein synthesis mechanism of human cells could have unforeseen consequences? Of course. Pretty much everything in medicine has unforeseen consequences. The question is--is the risk worth it? I think the answer is obviously yes.
And BTW the Covid vaccines aren't overnight successes--the work started with SARS, or maybe sooner--I don't know the whole history--so that's nearly 20 years ago. The big breakthrough came years ago when they figured out how to modify mRNA to create a stable version of the spike protein. When new vaccines are developed most of the time is spent in figuring out how generate antibody responses in cell cultures, then animals, then conducting clinical trials looking first at safety, then optimal dosing schedules, then doing phase 3 trials for non pandemic diseases that take a long time for enough people to get sick from less common diseases in order to generate valid results. In the case of Covid 19 the first steps went quickly not because of being rushed but because of the sophistication of gene sequencing, biosynthesis and the like compared to past decades. The part that was rushed, perhaps, was investigating alternate dosing and less rigorous cold transport regimens, which is why now we're debating one dose or two, full dose or half dose. (Note the Astra Zenica trial where some volunteers got a half dose by accident and seemed to do better than the full dose subjects.) The phase 3 trials were fast because--it's a pandemic. No shortage of people getting sick.

They told me in med school all the biochemistry would be useful my daily practice. This is the first time in nearly 50 years that I've had to think about it.

I appreciated that - esp. the perspective. Thanks.

**Ottime** · 01-06-2021, 10:38 PM

Same. Thanks goat.

**old goat** · 01-06-2021, 11:11 PM

Welcome. I hope I got it close to right or if not Mofro or someone else will straighten me out.

**Yonder_River** · 01-07-2021, 01:36 AM

Originally Posted by splat

Thought I heard somewhere that there's now an oxygen shortage happening.
Serially considering having a tank delivered in case I got this shit.
That's about all you can do other than eat aspirin and pepcid for home care from what I've heard.

Just buy an oxygen concentrator with a nasal cannula.

**The AD** · 01-07-2021, 09:14 AM

Originally Posted by splat

Tested negative. Stoked. I am blown away that, given the level of exposure I got, I apparently don't have it.

I'm gonna get an antibody test.

That's awesome, splat!

**summit** · 01-07-2021, 09:32 AM

The idea of EMS working an arrest on scene until ROSC (return of spontaneous circulation) otherwise terminating care at scene is considered progressive standard of care that leads to better outcomes with few exceptions. LA EMS protocols already call for working cardiac arrest on scene vs transporting to hospital while in arrest. Exceptions are unusual (e.g., hypothermic arrest/cold water drowning).

https://jamanetwork.com/journals/jam...stract/2770622
https://www.ncbi.nlm.nih.gov/books/NBK541113/
https://file.lacounty.gov/SDSInter/d...2018-05-30.pdf

**fastfred** · 01-07-2021, 09:36 AM

Originally Posted by Yonder_River

Just buy an oxygen concentrator with a nasal cannula.

I just listed mine on craigslist in california for three grand I'll probably shit the bed without it but 3 grand is 3 grand

**Mazderati** · 01-07-2021, 09:40 AM

Just get two funnels and stick the small ends in your nostrils. Same thing.

**old goat** · 01-07-2021, 10:34 AM

Originally Posted by Summit

The idea of EMS working an arrest on scene until ROSC (return of spontaneous circulation) otherwise terminating care at scene is considered progressive standard of care that leads to better outcomes with few exceptions. LA EMS protocols already call for working cardiac arrest on scene vs transporting to hospital while in arrest. Exceptions are unusual (e.g., hypothermic arrest/cold water drowning).

https://jamanetwork.com/journals/jam...stract/2770622
https://www.ncbi.nlm.nih.gov/books/NBK541113/
https://file.lacounty.gov/SDSInter/d...2018-05-30.pdf

Thanks for clarifying that. The ambulance policy is generating a lot of unjustified hysteria in the media. (There's enough justified hysteria, we don't need the unjustified kind.) No reason to bring dead people to the hospital.

**seano732** · 01-07-2021, 02:04 PM

Just went to my first Covid funeral today....Family only inside the church, everyone else sat in their cars and listened over the radio....Retired firefighter who I worked with years ago. 58 years old. Spent 21 days in the ICU, the last ten on a vent and never came back...Fucking brutal. RIP GS, you will be missed......

**The AD** · 01-07-2021, 02:17 PM

Originally Posted by ill-advised strategy

Apparently with transit ratfucked, and wfh, and outdoor restaurants, parking in nyc has gone from difficult to impossible.

This reminds me of the novel London Fields by Martin Amis. Has anyone else read it? Everyone is more or less prepped for the end of the world and start double, triple parking or just leaving their car in the middle of the road. Sort of prescient on Amis' part.

**frorider** · 01-07-2021, 06:02 PM

Originally Posted by The AD

This reminds me of the novel London Fields by Martin Amis. Has anyone else read it? Everyone is more or less prepped for the end of the world and start double, triple parking or just leaving their car in the middle of the road. Sort of prescient on Amis' part.

My avatar should answer your question

**Yonder_River** · 01-07-2021, 06:23 PM

Originally Posted by fastfred

I just listed mine on craigslist in california for three grand I'll probably shit the bed without it but 3 grand is 3 grand

Uh, ok fred. I'm assuming you're being funny, but if anyone wants one you can get them for under $500.

https://oxygensolve.com/

**fastfred** · 01-07-2021, 08:08 PM

Originally Posted by Yonder_River

Uh, ok fred. I'm assuming you're being funny, but if anyone wants one you can get them for under $500.

https://oxygensolve.com/

just here for the laughs fuck being serious about anything in life whats the point
but yeah mine cost me a grand it's a cadillac don't go cheap on oxgen wthout it you die you know 60 ft of hose so I can walk around my house and shit
I like puttin it on 5 liters and going over to the fire and stoking the fire it's like smoking in bed with oxgen

**Ted Striker** · 01-08-2021, 11:32 AM

Here we are 14 days from xmas and my county just reported 171 new cases as a result. That's an all time record for us. After 10 months to figure this shit out.

Goddamnit, Americans are stupid.

**gretch6364** · 01-08-2021, 11:32 AM

Originally Posted by bennymac

Attachment 356619

Attachment 356620

Attachment 356622

from the trenches of battling covid

I read back two pages and didn't see this brought it up...if it was further back my apologies, because the thread was discussing this, so it probably was already...but

Healthcare workers on the front line are seeing the truth of who COVID is killing, etc., and yet it appears there is a pretty huge chunk of healthcare workers declining the vaccine. A bunch of article in the news about it today. There just seems to be more to all this then what one would think in a deadly pandemic.

**rod9301** · 01-08-2021, 12:11 PM

It took 25 days from first symptoms to when i for a negative crp test.

Sent from my Redmi Note 8 Pro using Tapatalk

**CarlMega** · 01-08-2021, 12:34 PM

.......

**Dantheman** · 01-08-2021, 01:03 PM

Friend's sister died yesterday. She had some kind of autoimmune disease and a number of underlying health problems, but the proximal cause of death was COVID-caused pneumonia.

**Lvovsky** · 01-08-2021, 01:15 PM

Originally Posted by Dantheman

Friend's sister died yesterday. She had some kind of autoimmune disease and a number of underlying health problems, but the proximal cause of death was COVID-caused pneumonia.

Vibes to your friend

**pureantigravity** · 01-08-2021, 03:23 PM

Originally Posted by gretch6364

I read back two pages and didn't see this brought it up...if it was further back my apologies, because the thread was discussing this, so it probably was already...but

Healthcare workers on the front line are seeing the truth of who COVID is killing, etc., and yet it appears there is a pretty huge chunk of healthcare workers declining the vaccine. A bunch of article in the news about it today. There just seems to be more to all this then what one would think in a deadly pandemic.

see https://www.tetongravity.com/forums/...11#post6189311

**pureantigravity** · 01-08-2021, 03:26 PM

Originally Posted by Dantheman

Friend's sister died yesterday. She had some kind of autoimmune disease and a number of underlying health problems, but the proximal cause of death was COVID-caused pneumonia.

Vibes as well.

**LongShortLong** · 01-08-2021, 03:26 PM

Originally Posted by gretch6364

I read back two pages and didn't see this brought it up...if it was further back my apologies, because the thread was discussing this, so it probably was already...but

Healthcare workers on the front line are seeing the truth of who COVID is killing, etc., and yet it appears there is a pretty huge chunk of healthcare workers declining the vaccine. A bunch of article in the news about it today. There just seems to be more to all this then what one would think in a deadly pandemic.

There's a thought virus going around too... widespread infections, immune system unable to clear it.