Results 33,451 to 33,475 of 41810
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01-23-2021, 06:06 PM #33451
If it were me, and speaking as a veritable robot (aside from losing my shit on TGR from time to time), I'd let the emotional argument win. Living arrangements are emotional things.
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01-23-2021, 06:22 PM #33452
I'd get tested if I were them as there is a significant chance they got it if they wore the basic cloth masks and in a closed room. If testing is not drive up, I would probably wear a mask with a filter.
My brother and family currently have it. As far as he can tell he gave it to his running buddy earlier this week when they spent an hour together. Never inside and just running a few feet away side by side. That type of spread caught me off guard and I have a healthier respect for outdoor situations now.
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01-23-2021, 07:28 PM #33453My brother and family currently have it. As far as he can tell he gave it to his running buddy earlier this week when they spent an hour together. Never inside and just running a few feet away side by side. That type of spread caught me off guard and I have a healthier respect for outdoor situations now.
RE the family: Will a test be corrupted if they have been vaccinated?I have been in this State for 30 years and I am willing to admit that I am part of the problem.
"Happiest years of my life were earning < $8.00 and hour, collecting unemployment every spring and fall, no car, no debt and no responsibilities. 1984-1990 Park City UT"
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01-23-2021, 08:00 PM #33454
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01-23-2021, 08:02 PM #33455
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01-23-2021, 08:13 PM #33456lysterine
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What's the currently understood lag time between an exposure and becoming infectious to others at this point? 2-10 days?
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01-23-2021, 08:45 PM #33457
According to Mofro no. I asked that question. The test detects nucleic proteins, not the spike proteins the vaccine produces.
A friend of ours, vaccinated twice (over 65, does PT in nursing home) who my wife walks with--distanced, masks, just tested positive. One data point re the "does the vaccine prevent transmission" question. Possible that she acquired the virus while the second dose was still ramping up, but the first dose obviously didn't prevent it. The friend is asymptomatic.
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01-23-2021, 11:08 PM #33458
It sure would be nice to hear that someone is tracking that, testing her daily, etc. Feels like doing a phase 3 via mass rollouts as you've described would be good until we lost all the data that wasn't collected. You know, the sort of basic thing we could have taken for granted until recently.
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01-23-2021, 11:16 PM #33459
Bunion, the question is more complicated, like much in the biology realm. It's actually a really good question.
Short answer is "probably" no, albeit theoretically possible.
Edit to add "almost certainly no" for reasoning at the end:
The subtlety exists in that there are several different CLIA-approved COVID19 tests out there, both nucleic acid (PCR) based as well as protein (antibody) based. In fact, Intermountain Health Care uses two different PCR assays, both in wide use, which target different parts of the SARS CoV2 transcript for detection (actually, one of the assays targets the spike protein, which is what is coded for by both the ModeRNA and Pfizer mRNA vaccines).
In general, the extant PCR and antibody tests should target a part of the virus that isn't the same as that coded for by the vaccine, and therefore be able to distinguish between the two, but TBH, I can't tell if this is the case myself, as I can't actually find the primer sequences the PCR tests use, nor all the epitopes the different antibody tests are designed to recognize.
I can only assume that there's no overlap, 'cuz this issue should (almost certainly) have been anticipated by those designing and approving the tests. There's also redundancy and Quality Control built into the assays that oughta minimize the possibility of false positives in immunized patients.
I guess my point is that in a sense, its kind of a Wild West scenario in many ways, with plenty of unknowns and unexpected twists and turns, and the medical and scientific community is refining the approach as they go. Which is as it should be.Last edited by Tri-Ungulate; 01-23-2021 at 11:37 PM.
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01-24-2021, 12:29 AM #33460
We'd be relying on post-marketing surveillance, as is currently done with all drugs. Anyone vaccinee who tests positive is reported by their doctor or test facility along with whether they were symptomatic. It certainly wouldn't be as accurate as a randomized controlled trial but it should give a good idea fairly quickly if the efficacy is 20% or 80%. I don't believe either Pfizer or Moderna has done routine follow up testing after the second dose, have they, or have they just not reported it---so even those trials were not as comprehensive as they could have been.
Scientists want science. They want data as precise as they can get it. Doctors want enough information to make or keep people well. I think the medical approach is what is required at this time. If we get the pandemic under control and the virus becomes endemic people can go back and do more careful studies--probably with comparative controls, not placebos.
And it's not just the thousands dying every day or the tens of thousands of cases. It's also the people who will never get sick will have their lives ruined by the economic catastrophe who deserve a more aggressive approach.
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01-24-2021, 12:59 AM #33461
Don't get be wrong, I think you're right about what should happen. There are a lot of kinds of useful data, as AstraZeneca has obviously argued successfully elsewhere. I just expect we've gone far enough down this road that now we'll look to add 2 more vaccines to emergency use and continue the emergency for as long as it takes. At least, that looks like the near-term plan--sure would be nice to be wrong, but even with the will, how fast can the ship be turned?
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01-24-2021, 05:49 AM #33462
Keep the restrictions in place in the meantime, a modeling attempt says
https://www.nytimes.com/interactive/...e=articleShare
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01-24-2021, 06:53 AM #33463Banned
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What restrictions? I live in a county with the highest incidence rate in the state and it looks distressingly like "business as usual" around here. Big crowds, long lines, shitty mask compliance, a total disregard for social distancing, etc. Your odds of getting COVID here now are about 1000x higher than your odds of getting a vaccine.
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01-24-2021, 08:29 AM #33464
Restaurants are open for full occupancy in person dining?
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01-24-2021, 10:46 AM #33465
@glade, where did you move to again?
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01-24-2021, 10:49 AM #33466
Freedom County in the Wuhan District I think.
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01-24-2021, 11:04 AM #33467
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01-24-2021, 11:07 AM #33468
Bunion, what are the test sites like where your sister and BIL would get tested? The main one here is drive thru, very low exposure risk......
What we have here is an intelligence failure. You may be familiar with staring directly at that when shaving. .
-Ottime
One man can only push so many boulders up hills at one time.
-BMillsSkier
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01-24-2021, 01:40 PM #33469
What disturbing to me is the scale of societal burn-out. Many SMEs predicted that we will be entering the worst of times now, and they are now saying that their predictions are ringing true (easy prediction), but shit keeps opening up more and more. High schools, restaurants, and other indoor venues. Heard about restaurants in Chicago? Small bubbles/pods are opening up. New president, implementing actual solutions, etc., people are letting their guard down.
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01-24-2021, 02:04 PM #33470I have been in this State for 30 years and I am willing to admit that I am part of the problem.
"Happiest years of my life were earning < $8.00 and hour, collecting unemployment every spring and fall, no car, no debt and no responsibilities. 1984-1990 Park City UT"
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01-24-2021, 02:20 PM #33471
It's inevitable. Human beings are social creatures.
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01-24-2021, 02:56 PM #33472click here
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Myocarditis (heart injury) in 60% of post-Covid athletes. Study shows
Somewhere after the 51 minute mark, Dr. Seheult says usual treatment is to avoid exertion until you're good and sure the heart muscle is back to normal. Listen to your own doc.
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01-24-2021, 03:40 PM #33473click here
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I think CDC is saying something like this. I also think the evidence shows about 20% are infectious after 10 days. Sorry, no reference handy. Some international or national health body should have this evidence.
And to Bunion's concern, if the councilor was in fact infected the previous day, they most likely weren't yet infectious when your sister and BIL visited. Ofc, some folks are less proactive about notifying contacts of exposure, so councilor could have been exposed earlier, and infectious earlier. I commend that councilor for demonstrating honest and proactive behavior, would hire.
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01-24-2021, 03:48 PM #33474lysterine
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LSL, is your understanding earliest infectious date is usually 2 days then, post-exposure?
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01-24-2021, 04:45 PM #33475
Same here. When I got my test I never left my vehicle. Pulled in to first lot, rolled down my pass window, woman fully PPE’d up like an astronaut handed me instructions and a vial. Parked, filled the vial with saliva, followed instructions to add some kind of fluid, shake, call phone number and drive to next lot to drop off the vial to another astronaut.
No exposure to anyone.
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