Results 21,151 to 21,175 of 41810
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06-25-2020, 06:03 PM #21151
Mobility would seem to be a key factor in virus spread. In Santiago, one of the most "contagious" cities in the world right now, after 5 weeks of lockdown, mobility has only dropped 35%. That varies from only 24% in poorer districts, to 50% in richer ones, when it should be 60-70%.
Chile now has almost double the number of confirmed cases per million of the USA, and Santiago triple. Positives represent 1.3% of the country population, and 2.5% in Santiago. USA is 0.8% with almost double the rate of testing.
https://santiagotimes.cl/2020/06/23/...rosses-250000/
"Carabineros reported the detention of 17,321 citizens who did not comply with the quarantine measures, between June 15 and 21.
Of the total number of people who were detained, 12,010 (69.3%) were for crimes against public health, 6,962 for traveling outside curfew hours, 4,805 for curfew hours and 243 for other crimes against public health. Among those captured, the profile corresponds mainly to people between 18 and 30 years of age, mostly men."
This is just the ones they caught. Many thousands every day get "official" permits for 2 hours up to 2 weeks, maliciously, to visit friends/family, run non-essential errands, ride bikes, etc. My son, a neurologist, has to put up frequent no-shows, which would be false medical permits.
Here is a photo of the Santiago central market, where we used to love shopping for fresh fruit and vegetables, under quarantine, where only "wholesalers" with permits are allowed.
And more from the poorer districts
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06-25-2020, 06:09 PM #21152
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06-25-2020, 06:15 PM #21153
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06-25-2020, 06:26 PM #21154
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06-25-2020, 06:33 PM #21155
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06-25-2020, 06:40 PM #21156
You could go to LaGrande, with the highest rate of Covid in OR, thanks to the cabrons at the Lighthouse Pentecostal Church,
A story from a resident who got it from those pendejas. Fucked up on so many levels.
https://www.lagrandeobserver.com/cor...ce959242c.html
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06-25-2020, 06:43 PM #21157glocal
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- May 2002
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- 33,440
When antibodies are derived from plasma is that concentration the biggest factor in healing/immunity response? What effect would a direct blood transfusion from someone who, say, had detectable antibodies and the same blood type as a non-infected person who receives the transfusion, have with regard to forming an immunity?
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06-25-2020, 06:44 PM #21158Registered User
- Join Date
- Aug 2013
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- shadow of HS butte
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- 6,397
Our response to the COVID has been very similar to how we complete large infrastructure projects in this country.
Instead of telling people to suck it up and deal with a full closure for a couple weeks/months, we dick around and draw out the process for years. Imagine if in March we locked everything down, hard, for 2 months. Would that have been less impactful than dealing with it for the next 8 months, year, 2 years? Somewhat of a utopian view, just something that crossed my mind.
Think the reality is this isn't going away until it runs its course. Even if the country was locked down to the point where all current cases were no longer contagious, how would you prevent from coming in from other countries?
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06-25-2020, 06:47 PM #21159
I bet someone has already thought of that.
https://www.hematology.org/covid-19/...lescent-plasma
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06-25-2020, 06:58 PM #21160
Fear and Loathing, a Rat Flu Odyssey
Good point. During our “lockdown”, I wondered about whether a real Spain or Italian lockdown would have been more impactful in the long run. Would the economy be any worse off if we had done that then?
A full travel ban would accomplish keeping it out but that’s unrealistic.
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06-25-2020, 07:54 PM #21161
Casey E, appreciate the Chile updates. That is interesting.
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06-25-2020, 07:56 PM #21162“When you see something that is not right, not just, not fair, you have a moral obligation to say something. To do something." Rep. John Lewis
Kindness is a bridge between all people
Dunkin’ Donuts Worker Dances With Customer Who Has Autism
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06-25-2020, 08:16 PM #21163“When you see something that is not right, not just, not fair, you have a moral obligation to say something. To do something." Rep. John Lewis
Kindness is a bridge between all people
Dunkin’ Donuts Worker Dances With Customer Who Has Autism
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06-25-2020, 10:00 PM #21164
Regarding how antibodies/immunity works: the way I always explain it is think of when your body gets a new infection, it has to pick a lock on each virus to kill it. At first, it doesn't know the combination needed to open the lock. So the first thing your immune system does is go into a mode that tries out millions of combinations at once. This is called somatic hypermutation. Then, when it fi ds the correct combination, a signal is sent out and your body starts making millions of copies of that antibody with the correct combination. This is called clonal expansion. Those combinations are on two things: BCells which produce antibodies that bind to the virus and hopefully block it from entering cells, and TCells which find already infected cells and kills them so they can't make more copies of the virus. So while you are clearing the infection, you have lots of antibodies floating around. After it is cleared, your body keeps a memory of the combination that worked at a much lower level so if it sees the virus again, it can skip the lock picking (somatic hypermutation) and go right to clonal expansion.
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06-25-2020, 10:03 PM #21165
It remains to be seen if countries who have appeared to control the virus will continue to do so. It's way to soon for us to know if they will spike or not. The strategy of locking things down tight is based on the assumption that there will be a vaccine. If there isn't a vaccine it is quite possible that the virus will slowly burn through the population until herd immunity is reached (if in fact recovered people are immune).
We also don't know if there's anything seasonal about this virus and if it comes in waves is that biological on the part of the virus or behavioral on the part of populations.
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06-25-2020, 10:05 PM #21166
From the "this is nuts!" department:
The Lewis county sheriff (EWA) in response to the governor's mask mandate grabbed a bullhorn and told people not to be sheep by wearing masks.
I'm at a loss. Truly.“When you see something that is not right, not just, not fair, you have a moral obligation to say something. To do something." Rep. John Lewis
Kindness is a bridge between all people
Dunkin’ Donuts Worker Dances With Customer Who Has Autism
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06-25-2020, 10:06 PM #21167
So a vaccine is of course a product that I'd designed to get your body to pick a lock that has the same or similar combination as the real virus. So when you get infected, you also get to skip somatic hypermutation. Even if the combination isn't exact, maybe it's like 8 of 10 numbers so your body can pick the lock faster. Also might be the case with cross reactivity of similar viruses. Neutralizing antibodies are not helping your 3know how to pick the lock but are just the products of clonal expansion. They will help you fight off a current infection but not help you remember the combination for next time.
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06-25-2020, 10:09 PM #21168
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06-25-2020, 10:11 PM #21169
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06-25-2020, 10:14 PM #21170
If you're asking whether convalescent plasma used to treat active infection creates immunity, the answer is "possibly" although this has yet to be demonstrated AFAIK. Plasma contains B-cells (in addition to the antibodies themselves) from the donor. If the donor has established a memory response (which as you've seen in the news is not a foregone conclusion for recovered patients), then those B-cells should take up residence and continue to make anti-viral antibodies. However, in the cases where plasma donation is thought to be effective, no one knows if the response is mediated by the antibodies in the plasma or the B-cells that produce more once there.
Again, I'm not an immunologist.
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06-25-2020, 10:14 PM #21171“When you see something that is not right, not just, not fair, you have a moral obligation to say something. To do something." Rep. John Lewis
Kindness is a bridge between all people
Dunkin’ Donuts Worker Dances With Customer Who Has Autism
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06-25-2020, 10:15 PM #21172
Thanks, I enjoy the dumbed down explanations since I don’t come to TGR to think.
Pretty cool stuff
Sent from my iPhone using TGR Forums
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06-25-2020, 10:19 PM #21173
Good vaccines develop long term memory (think years and years). The lack of circulating antibodies (even low level) is a red flag that you've lost memory and need a booster assuming a vaccine is available. If you've lost memory and can't be boosted then you're obviously not immune to a new infection and your body has to "pick the lock" again as Lego put it.
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06-25-2020, 10:34 PM #21174
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06-25-2020, 10:55 PM #21175
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