Cool Science thread

[JayPowHound]

Man-Bear.

Then the porcines got involved...

.

[abraham]

Wait .... bears and people are having ...... SEX?!?!?

Yeah I had to go back to the headline and then click the link when I saw it. It's kinda cool to see similarities between our long term behavior and bears, at least in that way.

[Viva]

Here's a recent k00l study. Very close to the research I was conducting many years ago.

https://www.sciencedaily.com/release...0818135218.htm

Eating fructose appears to alter cells in the digestive tract in a way that enables it to take in more nutrients, according to a preclinical study from investigators at Weill Cornell Medicine and NewYork-Presbyterian. These changes could help to explain the well-known link between rising fructose consumption around the world and increased rates of obesity and certain cancers.

The research, published August 18 in Nature, focused on the effect of a high-fructose diet on villi, the thin, hairlike structures that line the inside of the small intestine. Villi expand the surface area of the gut and help the body to absorb nutrients, including dietary fats, from food as it passes through the digestive tract. The study found that mice that were fed diets that included fructose had villi that were 25 percent to 40 percent longer than those of mice that were not fed fructose. Additionally, the increase in villus length was associated with increased nutrient absorption, weight gain and fat accumulation in the animals.

"Fructose is structurally different from other sugars like glucose, and it gets metabolized differently," said senior author Dr. Marcus DaSilva Goncalves, the Ralph L. Nachman Research Scholar, an assistant professor of medicine in the Division of Endocrinology, Diabetes and Metabolism and an endocrinologist at NewYork-Presbyterian/Weill Cornell Medical Center. "Our research has found that fructose's primary metabolite promotes the elongation of villi and supports intestinal tumor growth."

The investigators didn't plan to study villi. Previous research from the team, published in 2019, found that dietary fructose could increase tumor size in mouse models of colorectal cancer, and that blocking fructose metabolism could prevent that from happening. Reasoning that fructose might also promote hyperplasia, or accelerated growth, of the small intestine, the researchers examined tissues from mice treated with fructose or a control diet under the microscope.

The observation that the mice on the high-fructose diet had increased villi length, which was made by first author Samuel Taylor, a Tri-Institutional M.D.-Ph.D. Program student in Dr. Goncalves' lab, was a complete surprise. And once he made the discovery, he and Dr. Goncalves set out to learn more.

After observing that the villi were longer, the team wanted to determine whether those villi were functioning differently. So they put mice into three groups: a normal low-fat diet, a high-fat diet, and a high-fat diet with added fructose. Not only did the mice in the third group develop longer villi, but they became more obese than the mice receiving the high-fat diet without fructose.

The researchers took a closer look at the changes in metabolism and found that a specific metabolite of fructose, called fructose-1-phosphate, was accumulating at high levels. This metabolite interacted with a glucose-metabolizing enzyme called pyruvate kinase, to alter cell metabolism and promote villus survival and elongation. When pyruvate kinase or the enzyme that makes fructose-1-phospate were removed, fructose had no effect on villus length. Previous animal studies have suggested that this metabolite of fructose also aids in tumor growth.

According to Taylor, the observations in mice make sense from an evolutionary perspective. "In mammals, especially hibernating mammals in temperate climates, you have fructose being very available in the fall months when the fruit is ripe," he said. "Eating a lot of fructose may help these animals to absorb and convert more nutrients to fat, which they need to get through the winter."

Dr. Goncalves added that humans did not evolve to eat what they eat now. "Fructose is nearly ubiquitous in modern diets, whether it comes from high-fructose corn syrup, table sugar, or from natural foods like fruit," he said. "Fructose itself is not harmful. It's a problem of overconsumption. Our bodies were not designed to eat as much of it as we do."

Future research will aim to confirm that the findings in mice translate to humans. "There are already drugs in clinical trials for other purposes that target the enzyme responsible for producing fructose-1-phosphate," said Dr. Goncalves, who is also a member of the Sandra and Edward Meyer Cancer Center. "We're hoping to find a way to repurpose them to shrink the villi, reduce fat absorption, and possibly slow tumor growth."

Dr. Marcus DaSilva Goncalves is a paid consultant and shareholder of Faeth Therapeutics which is developing therapies for cancer. Dr. Goncalves has received speaking and/or consulting fees from Pfizer, Novartis, Petra Pharmaceuticals and TruMacro Nutrition. The laboratory of Dr. Goncalves has received financial support from Pfizer.

[wooley12]

Well that explains it. When was eating large quantities of donuts, candy, malted shakes and table sugar with butter on white bread sandwiches trying to bulk up from 115# to to play on the varsity as a TE, I never gained any weight. And all those fools eating fruits and honey to be fit. HAH!

[crashtestdummy]

There are some interesting entries in this contest. https://www.jamesdysonaward.org/en-us/2021-entries/

[Dantheman]

Here's a recent k00l study. Very close to the research I was conducting many years ago.

https://www.sciencedaily.com/release...0818135218.htm

"A calorie is a calorie..."

There are some interesting entries in this contest. https://www.jamesdysonaward.org/en-us/2021-entries/

Indeed.

[Game Over]

You guys see China grew cotton on the moon (it came up in a biosphere and sprouted two leaves then froze)?

I’ll try to find the link.

Edit/ apparently it was from two years ago. I just saw it now on some farm feed…

https://www.popsci.com/china-moon-lander-cotton-plant/

[abraham]

You guys see China grew cotton on the moon (it came up in a biosphere and sprouted two leaves then froze)?

I’ll try to find the link.

Edit/ apparently it was from two years ago. I just saw it now on some farm feed…

https://www.popsci.com/china-moon-lander-cotton-plant/

You can buy space seeds from China.
https://www.superhotchiles.com/produ...v=7516fd43adaa

Total Eclipse-(Capsicum annuum)- This is one of four Space Chiles we are selling. The Space Chiles are from China. China sent seeds of many plant types into space and claim that cosmic radiation increased everything from germination and growing rates. Also increased productivity as well. The Total Eclipse is similar in shape to the larger Big Bang Space chile but is smaller in size and has more heat. It can be eaten green or red and has some sweetness especially when roasted. The chiles can get over 10 inches long. The Total Eclipse Space Chiles are great for roasting, stuffing, dried seasoning, stir fry and sauces. The Total Eclipse Chile plants grow over 3 feet tall. They need to be staked to support the weight of the chiles.

And speaking of plants this seems like a pretty cool idea. Using plants which accumulate certain metals as a possible way to mine. I wonder why the focus is on nickel? https://www.nytimes.com/2020/02/26/s...ants-farm.html
https://pubmed.ncbi.nlm.nih.gov/31739090/

[Viva]

I wonder why the focus is on nickel?

Change for a nickel, duh.

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[PB]

You guys see China grew cotton on the moon (it came up in a biosphere and sprouted two leaves then froze)?

I’ll try to find the link.

Edit/ apparently it was from two years ago. I just saw it now on some farm feed…

https://www.popsci.com/china-moon-lander-cotton-plant/

Not sure if Science.

[huckbucket]

More fusion progress. This one is a very big step forward. 30 watts to power a 20 tesla in a small high-temperature superconductor magnet. Leave it to those braniacs at MIT.

[ötzi]

There are some interesting entries in this contest. https://www.jamesdysonaward.org/en-us/2021-entries/

Definitely some cool ideas. "Omnom" wins best name award. "Coso" wins the nofuckingway would I use that award. "Hold on honey, I have to boil my balls for a few minutes."

[Dantheman]

More fusion progress. This one is a very big step forward. 30 watts to power a 20 tesla in a small high-temperature superconductor magnet. Leave it to those braniacs at MIT.

Fuck yeah. 2025 is a bold claim, that will be here in no time. 2025 is also the year that Rick Doblin thinks psilocybin will be become legal for medical use, could be a hell of a year.

[Dantheman]

The clock that takes 15 billion years to lose one second and can measure time slowing down due to gravity when it is moved just centimeters closer to the ground.

https://www.rawstory.com/what-the-wo...os-2654953202/

[crashtestdummy]

Electricity generating flooring.
https://www.woodworkingnetwork.com/t...%20electricity

[Harry]

An object just hit Jupiter.

https://www.space.com/jupiter-impact-flash-photo-video



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[BobMc]

Definitely some cool ideas. "Omnom" wins best name award. "Coso" wins the nofuckingway would I use that award. "Hold on honey, I have to boil my balls for a few minutes."

“So far, the procedure has been applied to animals. Therefore, the technical parameters are hypothetically transferred to humans.”

Somewhere out there a bunch of lab beagles are going, “Holy fuck my balls are killing me!!”

[crashtestdummy]

I'm like the technology, but do we really need to make the world whiter?

https://www.msn.com/en-ca/news/us/sc...?ocid=msedgntp

[Harry]

Uh oh… Chernobyl just woke up, and scientists don’t know why.

https://historyofyesterday.com/chern...p-74bedd5fc92d






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[ötzi]

I'm sure it's fine.

[PB]

Yep; proven technology, nothing can go wrong/fail.

[Dantheman]

Paging Summit....

Modern fission nuclear is certainly far, far safer than the Chernobyl reactors or anything else from that era. But, man, knowing that if something goes wrong it's fucked forever is heavy.

[stealurface831]

on the topic of russian radiation:

[ötzi]

I wonder how it's going in Fukushima these days.

[JimmyCarter]

I wonder how it's going in Fukushima these days.

Let me just check the webcam and…