Cool Science thread

[jackstraw]

^^^^That's rad.

Parkinson's may be caused by a bacterial infection

https://newatlas.com/medical/gut-bac...ted-treatment/
https://www.frontiersin.org/articles...3.1181315/full

Cool

[Dantheman]

The scope of ancient Mayan civilization has just been shown to be much larger than we previously believed.

https://www.msn.com/en-us/news/world...D=ansmsnnews11

[Dantheman]

LIGO back online after upgrades. Can now detect blackhole mergers up to 5 billion LYs away. Expected to detect at least one event per week.

https://www.livescience.com/space/bl...ions-ever-seen

[byates1]

uhh..wow..

[From_the_NEK]

While perusing YouTube for science content, be aware that a lot of new "science" channels are popping up that are mostly just a lot of AI auto created spam.

[Dantheman]

Paging huckbucket and Tri-U....

https://medicalxpress.com/news/2023-...-triggers.html

"Researchers at Baylor College of Medicine have discovered a crucial regulator of the anti-cancer immune response that could change the game in the fight against cancer. Published in the Proceedings of the National Academy of Sciences, the study shows that in animal models of breast and prostate cancer, eliminating the gene SRC-3, specifically in a type of immune cell called regulatory T cells (Tregs), triggered a lifelong anti-cancer response that eradicated the tumor without the typical side effects observed with other therapies.

Furthermore, transferring Tregs without SRC-3 to animals carrying breast cancer tumors also resulted in long-term elimination of the tumor without negative side effects. The findings encourage pursuing further investigations to determine the value of this approach to treat the human disease."

[Viva]

^^^ I met Bert O' Malley when I interviewed for grad school at Baylor, thirty-plus years ago.

I requested to meet with him.

His office was rather ornate, with green carpeting and fancy furniture, I seem to recall.

He didn't really want to talk to me, just gave me a lecture at his white board about his lab's then current work on steroid hormone receptors. Nonetheless, I was very interested in going to Baylor and joining his lab.

But following my next visits to UCSD and Rockefeller, I pretty much forgot about BCM.

[old goat]

Astronomers discovered a new supernova exploding in M1011 Pinwheel galaxy on May 19th.

My backyard amateur astronomer friend got a picture of it last night. The second picture is a blow up of the supernova on the left, on on the right the picture he happened to take of the galaxy on May 18

[J. Barron DeJong]

Not so cool science:



https://twitter.com/armanddoma/statu...sR_NcRK2VkCfkg

[From_the_NEK]

Not so cool science:



https://twitter.com/armanddoma/statu...sR_NcRK2VkCfkg

Tell me again why the hell are we trying to bring about the Terminator prophesy?

[huckbucket]

Paging huckbucket and Tri-U....

https://medicalxpress.com/news/2023-...-triggers.html

"Researchers at Baylor College of Medicine have discovered a crucial regulator of the anti-cancer immune response that could change the game in the fight against cancer. Published in the Proceedings of the National Academy of Sciences, the study shows that in animal models of breast and prostate cancer, eliminating the gene SRC-3, specifically in a type of immune cell called regulatory T cells (Tregs), triggered a lifelong anti-cancer response that eradicated the tumor without the typical side effects observed with other therapies.

Furthermore, transferring Tregs without SRC-3 to animals carrying breast cancer tumors also resulted in long-term elimination of the tumor without negative side effects. The findings encourage pursuing further investigations to determine the value of this approach to treat the human disease."

I love the smell of autoimmunity in the morning. Seriously though, messing with Tregs has potential for anti-tumor immunity (see ipilimumab), but has already shown tox issues that this new approach will have to overcome. Specifically, Tregs are there to control the activitity of cytotoxic T-cells (CD8). If you remove that check in the tumor microenvironment, that's great because over-abundance and/or over-activation of Tregs is associated with immune suppression in tumors. However if you do that systemically, you'll have aberrant CD8 T-cell activity. Mice aren't good for modeling that kind of thing.

[Supermoon]

Not so cool science:



https://twitter.com/armanddoma/statu...sR_NcRK2VkCfkg

https://twitter.com/Phil_Lewis_/stat...744253954?s=20

National eating disorder group has to shut down its chat bot for giving dangerous advice.

Color me shocked

[Supermoon]

A bunch of astrophysicists have been teasing a big announcement tomorrow that came from their pulsar timing arrays.

https://twitter.com/hankgreen/status...975394305?s=20

[gravitylover]

In a major discovery, scientists say space-time churns like a choppy sea

https://www.washingtonpost.com/scien...ound-nanograv/

So there are ripples in the space-time continuum. Ehh, we knew that, right?

[Supermoon]

That thread I linked above has a good update about the findings.

Apparently it confirms a lot of gravitational wave stuff that was only theorized, and hints to the existence of many more super-massive black holes than we first thought.

I think the real excitement is about the method and where it can go I. The future, some of which is discussed in that thread.

[Buster Highmen]

[PB]

Intriguing. Curious to know how they deal with storms.
Place enough of them and slow ocean heating!

[ötzi]

^^ That's pretty cool. Also wonder about big storms.

[Buster Highmen]

Yeah, I was wondering about storms too.

They're testing them off the coast of Scotland which has pretty rough seas. Maybe in big storms, since they're close to Scotland where folks aren't as upset by men in skirts, they'll protect them with legions of drag shark story hours?

[huckbucket]

This seems to be a big deal. I know nothing about it ...

https://twitter.com/alexkaplan0/stat...44616528453633

[skaredshtles]

This seems to be a big deal. I know nothing about it ...

https://twitter.com/alexkaplan0/stat...44616528453633

If this pans out, it would be fuckin' *enormous.*

[EWG]

If this pans out, it would be fuckin' *enormous.*

Sure would, but right now it feels a little theranosy to me. Person who published the original paper is raising millions for a for-profit company, and although those researchers just said they verified an important piece of the original data it seems like they are still pretty far away from actually producing a room temp superconductor.

[PB]

Theranosy ...... I l ike it! Much better than Cold Fusiony.

[altacoup]

That would be mind boggling game changing tech. I’m sure that lab techs are racing to recreate the research. Can’t figure out what the company is from Twitter

[ghosthop]

^^Same day as more fraudulent papers are announced by the University of Rochester researcher that previously published he achieved ambient temperature superconductivity. I would wait and see on this one.