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  1. Replies
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    Read this last week then lost the link- ...

    Read this last week then lost the link-

    https://www.brookings.edu/blog/future-development/2020/03/23/a-mortality-perspective-on-covid-19-time-location-and-age/
    ...
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    That Nature paper from 2015 is the one the...

    That Nature paper from 2015 is the one the conspiracy theorist seized on about Sars-2 being man made.

    "no one could have known"
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    Mooeuthanasia seems like the least of our...

    Mooeuthanasia seems like the least of our problems right now.
  4. Poll: You know when I drink alone, I prefer to be by...

    You know when I drink alone, I prefer to be by myself. One bourbon, one scotch, one beer and all that.
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    I'm trying to drink away the part of the day that...

    I'm trying to drink away the part of the day that I cannot sleep away.- Modest Mouse
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    I just don't have #'s on a % infection rate of...

    I just don't have #'s on a % infection rate of Covid-19 positive with only GI involvement. But fecal samples are often positive for viral RNA and live virus has been found in these samples ...
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    Essencelessly I'm chained to the ole'factory. But...

    Essencelessly I'm chained to the ole'factory. But I'm looking for some wiggle room.
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    Just postulating as I'm not a clinician but it is...

    Just postulating as I'm not a clinician but it is possible that GI symptoms are larger part of systemic infection as opposed to just lung involvement, secondary organ infection etc and so are are...
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    soooo if we don't park at the TH's... we good? ...

    soooo if we don't park at the TH's... we good?

    I have a letter that sez I'm essential.
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    Something to digest. ...

    Something to digest.

    https://www.mcknights.com/news/clinical-news/gi-symptoms-found-in-nearly-half-of-patients-with-covid-19-new-study-finds/
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    How long will it go on? 322513

    How long will it go on?

    322513
  12. Thread: Cheer up

    by Mofro261
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    yeah and thanks for lodging "If This Is it" back...

    yeah and thanks for lodging "If This Is it" back in my brain. Damn you COVID-19!!!
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    We just passed China, USA #1!

    We just passed China, USA #1!
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    whoa whoa whoa. That doesn't say only 20% are...

    whoa whoa whoa. That doesn't say only 20% are symptomatic, it say undocumented, asymptomatic, OR mild symptoms accounted for 86% of the cases. That was also prior Jan 23 in China, and before travel...
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    https://www.npr.org/2020/03/25/820595489/why-germa...

    https://www.npr.org/2020/03/25/820595489/why-germanys-coronavirus-death-rate-is-far-lower-than-in-other-countries


    Early testing, frequent testing, more widespread and continued testing. And a...
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    I've been commuting like it's 1999.

    I've been commuting like it's 1999.
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    that graph y axis is #cases total so it can only...

    that graph y axis is #cases total so it can only go up or flat with time.
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    Its still OK to make eye contact.

    Its still OK to make eye contact.
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    I do upstream R&D for infectious disease...

    I do upstream R&D for infectious disease diagnostics and have been punching in on the covid clock since late January. We went to mandated no time off end of last week. I design the major biological...
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    mmm yes and no depending on the temporal...

    mmm yes and no depending on the temporal component. The antibody test is more likely to be positive (d7+ post symptom onset) the further away from the initial infection the patient is, since it...
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    "The butterfly effect in chaos theory underscores...

    "The butterfly effect in chaos theory underscores the sensitive dependence on initial conditions, highlighting the importance of even a small change in the state of a nonlinear system."
  22. Is the tank market fully stocked?

    Is the tank market fully stocked?
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    evO7zqllwH0 New York, New York I won't go...

    evO7zqllwH0

    New York, New York
    I won't go back
    Indelible reminder of the steel I lack
    I gave you seven years
    What did you give me back
    A jaw-grind, disposition to a panic attack
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    Chamber Bros - Time Has Come Today CsBwBct0_5U

    Chamber Bros - Time Has Come Today

    CsBwBct0_5U
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    going for the "couch-lock down"

    going for the "couch-lock down"
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    didja read the link? "The decision comes a day...

    didja read the link?

    "The decision comes a day after a Boeing worker died of a COVID-19 infection. The company said Sunday that 29 of its employees had been confirmed to have the disease, 24 of...
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    I was gonna ask if you guys were working with...

    I was gonna ask if you guys were working with live virus HTFB for the pos control, but sounds like synthetic RNA from what you described.
  28. I have been spending 6 days/week working on...

    I have been spending 6 days/week working on sars-coV-2. It was nice to get out and reflect a bit yesterday with some uphill social distancing.
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    I was going to say the same thing, the virus...

    I was going to say the same thing, the virus probably can't last minutes without a hydration shell, resp droplets should be on micron size.

    We sterile filter virus like particles thru 0.2um...
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    Send me your blood, I need samples to test.

    Send me your blood, I need samples to test.
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    Flaviviruses (dengue, zika, west nile,yellow...

    Flaviviruses (dengue, zika, west nile,yellow fever, JEV, SLEV, etc) and Alphaviruses (Chikungunya, Eastern Equine Encephalitis Virus, Western-EEV, Venezuelan EEV) and others are spread by the...
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    That is "Point of care" if you have access to one...

    That is "Point of care" if you have access to one of Cepheid's machines at your point of care. But 5,000 Genexpert devices in the US now, somewhat low processing as I remember 2/4/16 samples at a...
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    3 mos to 100,000 infections 12 days later...

    3 mos to 100,000 infections
    12 days later 200,000 infections
    4 days later 300,000 infections
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    All in to go all out.

    All in to go all out.
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    have a friend who's 83 yro dad is COVID-19...

    have a friend who's 83 yro dad is COVID-19 positive at a nursing home in Central Oregon, not looking good.
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    flu is a known entity and estimates are 1/5 to...

    flu is a known entity and estimates are 1/5 to 1/6 people got it this season, fatality rate <0.1%. Sars-CoV-2 is just as transmissible and possibly more, but as the outbreak is still in it's infancy...
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    https://www.sciencemag.org/news/2020/03/new-blood-...

    https://www.sciencemag.org/news/2020/03/new-blood-tests-antibodies-could-show-true-scale-coronavirus-pandemic

    link to non-peer reviewed pre-print:
    ...
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    tried to get that to catch on in the Rat flu...

    tried to get that to catch on in the Rat flu thread but no takers.
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    Earworm is going to get you. CZkjeJKBI0M

    Earworm is going to get you.

    CZkjeJKBI0M
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    I've been pretty stressed for several weeks to...

    I've been pretty stressed for several weeks to get things done at work with an ever heightened urgency. Really trying to have both a lab based ELISA and rapid Ab assays ready by mid-April.
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    Marijuana dispensaries are deemed 'essential' in...

    Marijuana dispensaries are deemed 'essential' in LA, allowed to stay open during coronavirus order

    https://www.cnn.com/2020/03/20/us/la-marijuana-coronavirus-trnd/index.html
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    Last week my station played this set in order- ...

    Last week my station played this set in order-

    That's Life- Frank Sinatra
    Strange Days- The Doors
    End of the World as we know it- REM
    Gimme Shelter- Rolling Stones
    End of the World- U2
    Touch...
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    we gotta stay positive. FY3V4ObYRsA

    we gotta stay positive.

    FY3V4ObYRsA
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    Data from Gemany suggests the largest target...

    Data from Gemany suggests the largest target populations thus far are the 35-59 age bracket followed by 15-34. Younger target age= less acute disease overall.

    ...
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    A couple hundred pages ago in this thread I...

    A couple hundred pages ago in this thread I wanted to start a rumor that vaping lung disease was actually Sars-CoV2 laced in black market Chinese vape carts.
    ...
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    Maybe why 38% of hospitalizations so far in US...

    Maybe why 38% of hospitalizations so far in US are age 20-54.

    Obesity, Diabetes, high blood pressure, heart disease, then add Sars-CoV-2 to the LRT.
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    weird, still available for me. ...

    weird, still available for me.

    https://www.imperial.ac.uk/media/imperial-college/medicine/sph/ide/gida-fellowships/Imperial-College-COVID19-NPI-modelling-16-03-2020.pdf

    edit- didn't see...
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    he has some good points and it is important to...

    he has some good points and it is important to consider that 8/10 that do test positive will have mild disease. I'm not sure modeling on the Diamond Princess is relevent anymore because as of Mar17...
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    Aerosol and Surface Stability of SARS-CoV-2 as...

    Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1N Engl J Med. 2020 Mar 17.





    Sars-CoV-2 particles are ~125 nM, large side for viruses.
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    I think I posted this last week. ...

    I think I posted this last week.

    https://science.sciencemag.org/content/367/6483/1176?utm_campaign=toc_sci-mag_2020-03-12&et_rid=315389663&et_cid=3242935

    Immediately after Christian Drosten...
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