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  1. Replies
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    To add to the confusion, there is inter-assay...

    To add to the confusion, there is inter-assay variability for cT (between companies) in re: what constitutes a positive PCR result - noting the type of machine used along with the cT is really...
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    Evusheld is for people who can't mount an immune...

    Evusheld is for people who can't mount an immune response, since it's basically engineered long-acting SARS CoV2 antibodies. Some efficacy against omicron as well as the BA.2 variant.

    I'm sure...
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    Yeah, no, kinda, maybe. Yeah, an...

    Yeah, no, kinda, maybe.

    Yeah, an inappropriate, perhaps "hyper" immune response is postulated to be the underlying cause of the inflammatory cascade that can lead to significant morbidity and/or...
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    Yeah, but you're describing heart symptoms that...

    Yeah, but you're describing heart symptoms that are episodic. POTS is kinda rare, and only recently associated with SARS CoV2 infection, and may only happen intermittently in that situation. Which is...
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    From what little I can gather thus far, if you...

    From what little I can gather thus far, if you indeed do have SARS CoV2-related POTS, it's not life-threatening, as a real heart attack or arrhythmia might be. The caveat is that it's early days in...
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    WG, a few things. 'cuz it had to be said:...

    WG, a few things.

    'cuz it had to be said: whereas yes, supermodel159 is technically correct in that some individuals have experienced cardiac sequelae from SARS CoV2 vaccination, I should add...
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    The other manuscript cited in the NYTimes article...

    The other manuscript cited in the NYTimes article in re: T-cell response, which IMO has been an unappreciated piece of the puzzle:

    T cell responses to SARS-CoV-2 spike cross-recognize Omicron
    ...
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    Mebbe his career as a fry cook ain't panning out...

    Mebbe his career as a fry cook ain't panning out the way he'd hoped.
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    Thanks for that mofro. I did figure you guys...

    Thanks for that mofro. I did figure you guys woulda vetted the constructs, so I shouldn't have worried too much about that part, makes sense the proteasome complex eliminates misfolded products.
    ...
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    Theoretical problem is that if changing the mRNA...

    Theoretical problem is that if changing the mRNA vaccine to address a new strain's spike protein (or functional equivalent that serves to allow viral entry into the cell), there's no guarantee the...
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    Shinjuku motherfucker

    Shinjuku motherfucker
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    Mebbe scarred forever by inappropriate mag recs...

    Mebbe scarred forever by inappropriate mag recs for an Earthshine mascot.
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    Thanks mofro, you and Lego are the two posters I...

    Thanks mofro, you and Lego are the two posters I get the most mileage from on these threads.
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    To Vaccinate or Not---The Rat Flu Odyssey Continues

    Thanks Lego. I appreciate hearing updates from your team. Honestly it’s one of the few ways I can get a gestalt on T-cell response to the virus, recognizing that the data is preliminary and based on...
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    Yeah, it's pretty fucking weird that he'd go...

    Yeah, it's pretty fucking weird that he'd go through the trouble.

    Double weird since all he has is boilerplate alt-right COVID misinformation shitposting.

    Personally not a hudge fan of...
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    Simpsons Did It! 394854

    Simpsons Did It!

    394854
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    Nobody here is saying the CCP has been blameless...

    Nobody here is saying the CCP has been blameless in the COVID19 pandemic, certainly not myself. But really, this whole Xi kerfluffle is just manufactured outrage from the Faux Nooz talking head set,...
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    We’ll, if you’re actually in the trenches like...

    We’ll, if you’re actually in the trenches like MagUni or beaterd (sorry Austin, but skulking around your local ICU with phone in hand doesn’t count), stoopid alt-right memes don’t fly all that well....
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    Lulz, it's so fucking obvious what MF is trying...

    Lulz, it's so fucking obvious what MF is trying to peddle.
    Those unclean yellow peril virus engineers, bending the semantic agenda to extend their evil political ends, heaven forbid.
    Next, he'll...
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    394715

    394715
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    Right, KQ. But the "better efficacy"...

    Right, KQ.

    But the "better efficacy" argument of switching from Pfizer to ModeRNA is (at least to my knowledge) based on a fairly small study using relative increase in antibody titre as its...
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    Perhaps I haven't been paying close enough...

    Perhaps I haven't been paying close enough attention, but from what little I know, the relative response rates from the mix-and-match studies is entirely based on surrogate markers, primarily B-cell...
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    well, at least not for mAb administration. As a...

    well, at least not for mAb administration. As a risk factor, definitely.
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    TBH it's actually a "no" though you doubtless...

    TBH it's actually a "no" though you doubtless already know that.

    Once they're in the ICU, it's too late to administer monoclonal antibodies, at least to salutary effect.
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    Stupid is as stupid does, and sadly our ICU is...

    Stupid is as stupid does, and sadly our ICU is currently filled with science-denying stupidity (insofar as they deny the science behind vaccinations but somehow accept the science behind monoclonal...
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    I'm not Summit, but I stayed at a Holiday Inn...

    I'm not Summit, but I stayed at a Holiday Inn Express.

    Answer is yes, but primarily for individuals at risk for complications for either age- or comorbidity-related reasons.

    Edit to add: I...
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    He’s in the NFL thread defending Rodgers, of...

    He’s in the NFL thread defending Rodgers, of course.
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    And this is proof that teh TRGs have gone full...

    And this is proof that teh TRGs have gone full TTips.
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    LULz where does he think the monoclonal antibody...

    LULz where does he think the monoclonal antibody infusion therapy comes from?

    http://youtu.be/gGBdZcMc3i8
    ...as for corrupt bureaucrats and politicians...
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    Because Austin's sister's hairdresser saw...

    Because Austin's sister's hairdresser saw something about it on her Instagram feed on how it makes your balls go OW!

    387949
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    ...and a dentist, to boot. Anyway, if...

    ...and a dentist, to boot.


    Anyway, if there's any doubt that teh TRGs have gone full endstage-TeleTips this thread is proof.
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    Dude, it seems increasingly in your case it's...

    Dude, it seems increasingly in your case it's called #duhbutthurt.

    Give it a fucking rest, or as buttahflake would put it...
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    To Vaccinate or Not---The Rat Flu Odyssey Continues

    LOL as if he understands the difference. [emoji57]
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    I believe the term you want to use is "disappear"...

    I believe the term you want to use is "disappear" them.

    Hey, it worked for you in the '70s.
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    I thought it was Big Farmer.

    I thought it was Big Farmer.
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    Yup. Hey, Austin also posts funneh vidz...

    Yup.


    Hey, Austin also posts funneh vidz about furriners.


    Duh. The furriners of course.
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    My impression both from underlying biology (to...

    My impression both from underlying biology (to the limited extent that we understand it), there is no age bias for "long covid" seeing as it appears to be a form of persistent chronic...
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    With absolutely no data to support this, my...

    With absolutely no data to support this, my suspicion as a TRG dentist with some moderate immunology larnin' (from the interwebz, of course) is that the 2nd shot after initial infection and 1st shot...
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    I guess. But you and I know it's steroid-induced...

    I guess. But you and I know it's steroid-induced muscle, not morbid obesity.

    Guess he could invoke steroid-induced immunosuppression. Huh.

    ...and according to Deeb, he shouldn't even be...
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    Rogan is an entertainer, playing to his audience....

    Rogan is an entertainer, playing to his audience. Since he's vaxxed, and got monoclonals (which he really shouldn't have, if we're actually following protocols whereby only at-risk patients like the...
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    Yes, but that is generally in the outpatient...

    Yes, but that is generally in the outpatient setting.

    In the inpatient setting, especially in critical care, the team managing the patient can do a consultation, usually in person, but...
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    Yeah, I was just being facetious. But if the...

    Yeah, I was just being facetious. But if the patient leaves AMA that's on them. There is the issue of whether the accepting physician is willing to be responsible for a patient that is unstable for...
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    Exactly. Wagshul is not the patient's attending...

    Exactly. Wagshul is not the patient's attending physician. Looks like he's affiliated with a hospital about 30 miles from where the patient is currently being treated. He's a pulmonologist, so...
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    Inpatients, especially critically ill patients...

    Inpatients, especially critically ill patients requiring ICU care are managed by the inpatient/ICU team, and I am unaware that an outside physician can make an intervention that isn't agreed upon by...
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    AKA Mr. Gyptian

    AKA Mr. Gyptian
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    What, did Cawthorn also test positive? Oh wait,...

    What, did Cawthorn also test positive? Oh wait, he kicked a tree's ass.

    http://youtu.be/pm4gpYwwaCA
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    It's pretty disgusting, actually. We have a...

    It's pretty disgusting, actually. We have a pretty strict protocol on who gets antibodies: immunosuppressed automatically qualify, or you get points for age, sex, and comorbidities: if you score...
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    ^^ The "anecdote" comment coming from the person...

    ^^
    The "anecdote" comment coming from the person who posted about how his sister-in-law's Uber driver's hairdresser's Facebook post said something something something is pretty fucking rich.
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    Dude, your "not entirely joking" with your ...

    Dude, your "not entirely joking" with your

    is still bullshit, treating real lives (and deaths) like some kind of libertardian human ledger "cost of doing bizness".

    Also a Gen X'er I can laugh...
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    Hey asshole. You're joking about people who are...

    Hey asshole. You're joking about people who are dying. Do you realize that?

    You're also joking about overburdening a strained healthcare system, and end-costs that affect your very own...
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