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  1. Replies
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    The part I'm struggling with is balancing the...

    The part I'm struggling with is balancing the AE's with the benefit. We traditionally think of the benefit as the potential to reduce short term disease. However, if we think a little further into...
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    Should your 12 year old get vaxxed? It's not as...

    Should your 12 year old get vaxxed? It's not as straight forward as you might think. This guy is a well known curmudgeon, but he's got some good points.
    ...
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    Exactly. And this is the reason for the new CDC...

    Exactly. And this is the reason for the new CDC guidance. Just in case anyone thinks the CDC is being inconsistent, flip-flopping, etc. Takes time to collect and analyze data.
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    Shit dude. You a member of Mensa?

    Shit dude. You a member of Mensa?
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    Horseshit. The CDC has been preparing for...

    Horseshit. The CDC has been preparing for pandemic scenarios for at least 50 years.
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    Ohhh ... she's definitely still a favorite. ...

    Ohhh ... she's definitely still a favorite.

    https://i2.wp.com/unucycling.com/wp-content/uploads/2014/09/Emily-Batty-Canadian-Olympic-Cyclist-9-1.jpg?resize=628%2C837
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    Legit! Nice work Pickels.

    Legit! Nice work Pickels.
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    You've got another voice on your side. Aren't...

    You've got another voice on your side. Aren't you from Scripps (maybe I'm thinking of someone else)? The debate rages on.

    https://twitter.com/K_G_Andersen/status/1391507230848032772
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    Dumbing it down one step farther .... "we may...

    Dumbing it down one step farther .... "we may have a better way to treat the rare, yet severe adverse events that occur in what is otherwise a very safe vaccine"
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    I laffed at the part in bold. Can't say I...

    I laffed at the part in bold. Can't say I haven't done the same in the past although I always lemented the fact that I couldn't spell out FUCK. If you truly want to go nerdsville, I once created a...
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    As usual, there are really great opinions to...

    As usual, there are really great opinions to stand on as one formulates their own. This is one of them.

    https://blogs.sciencemag.org/pipeline/archives/2021/05/06/waiving-ip
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    You do realize that you're siding with "libreral...

    You do realize that you're siding with "libreral activists?" A good hot shower might wash that off.
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    If we just look at the furin site comparing the...

    If we just look at the furin site comparing the supposed ancestor (RacCS203) to SARS-CoV-2, then it would have taken an aa insertion and at least two mutations to convert a valine to an arginine...
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    David Baltimore weighs in; “When I first saw...

    David Baltimore weighs in;

    “When I first saw the furin cleavage site in the viral sequence, with its arginine codons, I said to my wife it was the smoking gun for the origin of the virus,” said...
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    Has the WHO put out anything worth reading from...

    Has the WHO put out anything worth reading from their on-site investigation into the lab?
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    I get the balanced approach, but back to the...

    I get the balanced approach, but back to the furin cleavage site in the spike. Evolution is really, really amazing, but that thing just smells super funny, codon-optimized and all. Says in the...
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    I get it, but I wouldn't have posted it if there...

    I get it, but I wouldn't have posted it if there wasn't some merit to the piece. The author did a really nice job. Closest to a smoking gun that I've seen.
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    I've got a fantasy of a Kate Courtney x Pauline...

    I've got a fantasy of a Kate Courtney x Pauline Ferrand-Prévot sandwich. Does that count?
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    The best piece I've read to date about the origin...

    The best piece I've read to date about the origin of the virus. Of particular interest is the discussion on the furin cleavage site. Has my eyebrows raised.
    ...
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    My wife hates my sense of humor.

    My wife hates my sense of humor.
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    I'd be willing to look at the data. Please post...

    I'd be willing to look at the data. Please post a link.
  22. Kudos to dad. That's awesome.

    Kudos to dad. That's awesome.
  23. We've done cascase, ampersand and jo. Might hit...

    We've done cascase, ampersand and jo. Might hit up hurricane but am open to ideas.
  24. Bringing my girls up there mid-June. We've gotta...

    Bringing my girls up there mid-June. We've gotta decide what to climb on this trip. Marcy is a stretch for their patience/fitness.
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    You might be confusing it with the Fiat Panda...

    You might be confusing it with the Fiat Panda launch party around the same time.
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    Oh shit bro! You were there too? Those fucking...

    Oh shit bro! You were there too? Those fucking ravioli! mirite?

    :rolleyes:
    :wink:
  27. Oh ... FUCK YOU!! Can't stop watching. The...

    Oh ... FUCK YOU!! Can't stop watching. The sequence at 4:30 was unbelievable.
  28. Replies
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    Ever heard of the saying "less is more?" You...

    Ever heard of the saying "less is more?" You need to take a deep breath.

    Couple of quick corrections to your post. Both Pfizer and Moderna harbor single-stranded RNA which means they will not be...
  29. You just know that's guuud. I use a 1:1 honey...

    You just know that's guuud. I use a 1:1 honey and dijon on salmon on the grill which is kinda the same thing really.
  30. Wait. What in the actual ... ? ...

    Wait. What in the actual ... ?

    http://www.reactiongifs.com/wp-content/uploads/2013/10/tim-and-eric-mind-blown.gif
  31. Although if you ask for a sub at a strip club you...

    Although if you ask for a sub at a strip club you might be surprised by what you get.
  32. It's an f'n sub. Not a hero. Not a grinder. ...

    It's an f'n sub. Not a hero. Not a grinder. Not even a hoagie or torpedo.
  33. Replies
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    There's quite a large body of data to delve into...

    There's quite a large body of data to delve into on this topic. Perhaps you should spend some time looking through abstracts on pubmed and let us know what you find.

    pubmed.gov
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    Surely that's gotta change with the CDC update on...

    Surely that's gotta change with the CDC update on outdoor mask usage. We've been full on riding/racing in groups already this year. Did my 5th race last night.
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    Effectiveness shouldn't be impacted although host...

    Effectiveness shouldn't be impacted although host immune response will likely be different for a replication-competent virus. Readministration (boosters) might be impacted. Pathogenic effects of...
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    Jesus Christ! Fuckin Ruskies. "The Sputnik V...

    Jesus Christ! Fuckin Ruskies.

    "The Sputnik V vaccine Ad5 vector is evidently replication competent. The makers apparently neglected to delete E1, so getting this vaccine means being infected with...
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    While those people were asymptomatic, I bet if...

    While those people were asymptomatic, I bet if you profile them for the whole range of covid-specific immune signals (Ab, B, T including subsets) you'd find signs of prior infection. In which case...
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    Yeah ... I think someone substituted piss for the...

    Yeah ... I think someone substituted piss for the milk in my cereal yesterday. My bad. Carry on.

    Tri-U is right though. Whatever you can dream up to investigate in the covid space (or the...
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    Wait. Your idea? You do realize how obvious...

    Wait. Your idea? You do realize how obvious that hypothesis is, right? Further, the Wheery paper referenced in that article (linked below) takes it one step further. Rather than explore a rather...
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    Serum antibody concentrations are an imprecise...

    Serum antibody concentrations are an imprecise predictor of protection. There are other immune signals to monitor that wouldn't be feasible for wide-spread use as was published and shared here...
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    Reposting. ...

    Reposting.

    https://www.scientificamerican.com/article/if-you-dont-have-covid-vaccine-side-effects-are-you-still-protected/
  42. Does the UC brewery have such a thing? 372623...

    Does the UC brewery have such a thing?

    372623

    372624
  43. Replies
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    The googs is your friend. ...

    The googs is your friend.

    https://www.sciencemag.org/news/2021/04/vaccines-can-protect-against-many-coronaviruses-could-prevent-another-pandemic
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    If you use these sorts of examples as proof that...

    If you use these sorts of examples as proof that science is not trustworthy than I sincerely doubt you understand how science works. Science moves on a continuum where evidence is directly...
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    I posted that. Wassup? ...

    I posted that. Wassup?

    https://www.tetongravity.com/forums/showthread.php/332958-Fear-and-Loathing-a-Rat-Flu-Odyssey?p=6298638#post6298638
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    Says it right there in Mofro's post; Of the 74...

    Says it right there in Mofro's post;

    Of the 74 fatal cases, 9 (12%) were reported as asymptomatic or the patient died due to a cause not related to COVID-19.

    4 month of tracking people aged 16...
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    Yeah, I think there's little doubt of that. ...

    Yeah, I think there's little doubt of that. Clinical trial data notwithstanding, the real world data from Israel using Pfizer is trending to a 90% reduction in infection rate comparing unvaccinated...
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    CDC officially tracking roughly 6000 breakthrough...

    CDC officially tracking roughly 6000 breakthrough cases where vaccinated individuals became positive outside of the 2-week post second shot window. CDC recognize that 6000 is likely inaccurate...
  49. Dude is so entertaining. Brilliant.

    Dude is so entertaining. Brilliant.
  50. Replies
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    If he's a client: up your pricing and make up a...

    If he's a client: up your pricing and make up a story about how you have to charge more to compete with the Chinese
    If he's a partner: go find a new one
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