Just to add two more: Did the J&J use the same sample period from the time of the (first) shot? And definition of success?

How many people will get the J&J and jump on a plane the next day? Having...

I don't see an answer for the OP, but it does contain at least one bit of wisdom:

...

Is there actually a trial underway for children or is that the soonest it could happen if they start one? Can't tell if this is priorities or trying not to state the obvious and hoping a bifurcated...

It's been a minute since the pic of the Chinese dude wearing a maxipad got all the attention, huh?

So true.

$85 and apparently available (lifetime purchase?)

https://narwallmask.com/

If you hook the intake to your seat's overhead air please post pics.

CA has their own variant, why not WI?

Like an eruption turned inside out. Awesome.

Uptick of two posts ago explained?

No judgement but, I mean, it stands to reason, right?

So...gearswap?

Lycra. It's the Lycra.

Were you up there yesterday Goldmember? I thought I spotted some black skis on the Face but I'm awful at remembering clothes colors.

All I have are some random thoughts so apologies in advance for their general uselessness.

Too many ethical arguments both ways for my little brain. The only thing that stands out, and I'm not...

Unfortunately the sarcasm wasn't lost, I'm just trying to be more diplomatic with people who claim stupidity. The "just" implies that no one ever gets more than a moderate improvement when in reality...

So you're saying you're adjusting your understanding to account for the mistake in your assumption? Are you removing the word "just" and accounting for the fact that some will also get "complete...

Foggy basin pushed the ceiling up for a minute or six between the hail and graupel. Halfway to a reset maybe? Ice under B- feels covered, at least.

364594

Sigworthy

At the risk of stating the obvious: now skiing. Highly recommended. Maybe sleeping first (so not technically now) but then definitely skiing.

Obviously I'm just spitballing here, so not really looking to take a firm position on it, either. The recent numbers out of Scotland and Israel were what got me thinking the mRNAs might already be...

Well played, sir

FIFY

I think it worked out. No idea what I'll think of this in a few more hours, but so far so good; just about to hour 5, skied from ~1.5-4.5.

It'll most likely kill me tomorrow, but my phone...

Like like no one yet. If I'm the first I'll update--but no GoPro footie.

Ok, Dr Two-dose, here's the question that keeps ringing in my head: if we're concerned about dropping down to one dose for mRNA's, should we also try to avoid the J&J/AZ vaccines because of their...

I want to go skiing right after Moderna #2 for a couple hours. Why's that a bad idea?

Yeah, I noticed you said Friday was busy, too. We must be hitting opposite times or places lately. Pretty sure the fog is an easy explanation--my wife wanted to avoid the racers so we never got to...

I worked with a guy who had been involved with the Q400 qualification in ~2012 and we discussed those props a bit. He said the qual standard was to finish the flight, not that all passengers must...

Ouch, glad that didn't end with something worse! That ice layer is sneaky. Last week I unwittingly pointed someone onto it just past B chute and got to watch her slide/scrape the 4" dust off the...

Think of it as a chance to do original exploring. A rare opportunity these days. Way easier than it used to be, and getting less rewarding as the challenge shrinks.

Depends on the objective. A more basic question would be whether or not capturing a multi-dimensional situation in a one-dimensional rating is the right goal?

The goal should be communication,...

Wishful thinking is one way to put it. Herd immunity threshold depends on behavior and interactions. It's like if we have five threads and some people read 1 or 2 but not all five: a meme or an...

Are you speaking the language they use to train the bots?

The ability to lay off employees if things don't go as expected actually encourages manufacturing to ramp up. Not as nice for the employees but less binding on the bean counters. If you make a...

There it is

Systemic change

For sure. Conversely, the randos on a message board are a little more like the general (no to say exactly "voting") public.

Interesting point about Fauci again--his ability to stay on the fences...

I don't know if we'll see a study on single doses here, but the ones in Israel (Lancet link above) and the UK (bumping second doses to 12+ weeks on everyone) should be of some use if we're paying...

Thanks for inspiring me to do the same. All you stupid fucks calling people names are being stupid and you need to knock it off. It's stupid because it's ineffective at achieving the exact thing you...

I should have just read the NEJM letter's chart slower, the details are straightforward. The sample size was kind of small to get very precise about efficacy numbers for the single week before the...

The whole problem with that line of thought is that we don't know duration of either 1 or 2 dose regimens. So we have no direct evidence that 2 will last longer than 1 or to be confident long term of...

Argument for skipping second doses (for a while, at least):



https://www.nejm.org/doi/full/10.1056/NEJMc2036242

Thoughts? Hopes? Unless this is garbage it seems like a huge leap compared to...

If NYT's opinion section is Maury, Glen Greenwald wants to be TMZ.

Greenwald, so...lemme guess, the fire extinguisher may not have killed him so the while thing about officer Sicknick being dead is just media exaggeration?

There are a lot of jobs that shouldn't be done in person until those people are vaxed--most because the job can be done otherwise. And first responders etc should have been eligible everywhere for a...

So a 75% reduction in viral load for Pfizer from 12-28 days after the first shot. Any similar study for Moderna anywhere? Lots of assuming the two are interchangeable--any exceptions?

Don't be fooled. The fear was always that it could be illegal for people to buy their way ahead in lines. That really hasn't happened. I mean, sure, in theory, but more people go to jail for touching...

Seriously the biggest challenge. I had my best day in months today while my wife took a car in for a recall and ran errands. Been 80% or so remote for almost 15 years but the pandemic somehow gave me...

Not that this justifies it, but maybe it tempers it a little:

Dinner partiers jumping the line is not all bad: if we self-selected based on concern about the virus (which is happening in a few...

You need to make the troll less obvious. No one seriously overestimates the popularity of two or the other PNW sports teams by that much.