Printable View
Quote:
Originally Posted by Gcooker
Canada/UK went with the OG strain and Ba1 this year for whatever reason...no idea if they are available.Quote:
Originally Posted by old goat
https://www.bmj.com/content/378/bmj.o2144
Sent from my SM-G991U1 using Tapatalk
Probably a good idea. Like some others here I felt pretty tired and useless all weekend after my flu/bivalent booster. No idea if that was from the shots or just waking up in a bed and realizing I am still living in shithole Iowa, but it was a thing.Quote:
Originally Posted by riser4
And the shingles kicked my ass both times...along with stomach issues.
Sent from my SM-G991U1 using Tapatalk
Getting my Pfizer bivalent and flu shot on Friday. Hoping to be one of the few that get some relief from long covid with this jab.
Quote:
Originally Posted by riser4
Plus you have to drop trou if you want a third shot.Quote:
Originally Posted by uglymoney
I hope it helps!Quote:
Originally Posted by Whiteroom_Guardian
That's never stopped me before.Quote:
Originally Posted by old goat
Pulling for you!Quote:
Originally Posted by Whiteroom_Guardian
No--it's the thought of it that had the nurse telling your doc no way.Quote:
Originally Posted by riser4
Heh. Actually, the nurse was all for it, Doc overruled. So there. But your quip made me chuckle, so full points for you. And, the day after that was my day to get my monthly shot in the ass from a different provider. So a different nurse got to see my ass. Poor soul.Quote:
Originally Posted by old goat
Here's a weird thing I noticed last week. I got a slight reaction to my monthly Emgality injection when I took it 4 days after the Pfizer booster and flu shot. Injection site burning and itching for a day and a half afterwards. It's a common side effect but not one I've experienced yet in the past 9 months of taking those Emgality injections. Thinking my body being at war with and forming more antibodies to the COVID variants and flu made me more susceptible to the stronger reaction I had to the Emgality.
Interesting you say that. My monthly is testosterone and I too noticed burning that I haven't noticed before, went away overnight. The T shot was about 18 hours after the Seasonal Flu and COVID-19 shot.Quote:
Originally Posted by SumJongGuy
When I was in the hospital the nurses were always chasing after me with a safety pin to close the back of my gown. Ruined my fun.Quote:
Originally Posted by riser4
Finally got the booster + flu this AM. My first appt was cancelled randomly day of by the pharmacy. Hoping this doesn't mess me up at all. Booster + flu October 2021 and I had no reaction at all.
https://www.cbc.ca/news/canada/calga...ovid-1.6613841
people refusing blood transfusions from Donors who got the vax but Canada does not register if the donor was vaxed
seems like a Darwin moment
Some people refuse blood transfusions because they're afraid of getting a disease from the donor. But in Canada, to get a blood transfusion, the donor has to tell the hospital whether or not he got any vaccines. So if you see that the donor got a vaccine, that means he's protected from that disease and can't give it to you. If you get your blood from someone who hasn't been vaccinated, you're taking a big risk!
Low dose naltrexone may offer some helped for some long-rona, but I haven't read it deeply
https://www.reuters.com/business/hea...ue-2022-10-18/
Osterholm update:
Expect more Covid in coming months
Get your boosters
Always wear n95 in public (he's ok with well-spaced outdoor dining)
Various variants showing immune evasiveness may reduce effectiveness of vaccines and treatments
https://www.youtube.com/watch?v=Fs_A...ate%3ACOVID-19
Health system is still short staff from pandemic. Expect crisis care for any health issue if we get a big Covid surge. Shortage of care homes means hospitals have nowhere to send patients and will fill faster as a result.
He also discussed social impacts of pandemic and its response. Survey says 20% of kids have lost a family member to Covid. Also noted the divisiveness some families and friends experience.
And briefly mentioned there's vaccine for monkeypox and high risk folks should get it.
So take care of yourselves and each other.
Man, navigating this by mask wearing at this point seems beyond pointless if you have kids in school and they aren’t wearing masks.
Meh, if you're immune compromised... or just really don't want to get sick go with the mask everywhere all the time indoors.
As long as community spread remains low (and it's pretty low here) and there is no alarming trend uptick.. hospitals/healthcare facilities aren't any more stressed than they were before COVID, more flu than COVID emergencies.. masks aren't going to be mandated again. It will have to be a total triage shitshow before masks are mandated again.. .. but I'd hope they go there BEFORE it gets that bad again... I doubt we will though..
So .... no body thinks a mask is a good idea for the flu?!?
Like I said.. "if you really don't want to get sick".. We'll see some folks keeping the masks for other threats even after COVID is all but gone (I can hope right?)Quote:
Originally Posted by PB
PreCovid I'd probably never consider wearing a mask in someplace like the airport during flu season or whatever. Used to wonder why the Asian tourists did it so frequently. But now, yeah, that makes a lot of sense to me. I have a poorly considered notion that travelers/vacationers have good odds of getting sick to/fro airport; admittedly I may be seeing patterns where there are none.Quote:
Originally Posted by PB
Y’all know what community spread is like in your area? Our data (northern CA) is pretty poor these days.Quote:
Originally Posted by SumJongGuy
My wife got Covid (Pfizer) booster and a flu shot yesterday. She felt fine last night, but woke up at 2 a.m. feeling like shit. Could hardly even hobble to the bathroom. It doesn't exactly make me want to get one, but I will...
Ymmv. I was fine with the Pfizer bivalent and seasonal flu given same day, just a little passing odd sensation for a few hours 18 hours later. Your wife might actually have flu or COVID.Quote:
Originally Posted by The AD
I really meant more ... community impact... i.e. I live near the hospital.. If I see ambulances stacked up outside and/or know they're having to stop allowing visitors, telling family to wait in the parking lot instead of in waiting rooms that are currently filled with patients.. That's what I think of as high level community spread.Quote:
Originally Posted by bodywhomper
I suspect the only way the epidemiologist can track true community spread some is the sewer samples... home testing, asymptomatic folks.. No other way to really know the % of infected folks other than the % of infected shit and piss..
No, she always reacts badly to vaccines.Quote:
Originally Posted by riser4
Got Moderna and the flu shot yesterday - pretty achy and a little fever and a slight headache, not horrible compared to my first 2 shots.
Sent from my iPad using TGR Forums
+1. Had a double shot at CVS at 8pm so I could just sleep it off. Mild nausea and other symptoms. Good to go now. Flu shot arm hurts.Quote:
Originally Posted by teleee
Booster+flu last night. Feel pretty shitty today, but it gave me an excuse to take the day off work and watch rampage live, so could be worse. I had covid in May and it took 6 weeks to get over it fully, FTS.
My wife says she's about 60% today after being completely bedridden yesterday.
I'd say 60% at best today. Woke up multiple times last night drenched in sweat and peed a ton, full bladder every hour like clockwork. Lymph node in my left armpit swelled up HUGE overnight and hurts like hell.
Boosted 5th on Wed (incl flu)…headache and sleepy for about 8hrs, then back to normal
I got mine yesterday afternoon and tossed and turned a lot last night, but didn't feel awful overall. I swam this morning and now my arm isn't even sore. I feel just a slight bit queasy, but pretty much back to normal other than that.
Boosted a week or so ago. Good all day but uncontrollable chattering chills in the middle of the night and super sore arm in the morning. Dodged the headache luckily. The chills made me chuckle I was shaking so badly for a bit. Definitely not as bad as shot number 2 went for me by a long shot tho
Read deeply;) We prescribe naltrexone for all sorts of stuff now. Obviously narcotic overdoses, but also alcoholism and some for obesity with particular characteristics.Quote:
Originally Posted by summit
Hypothesis in terms of long covid may have anti-inflammatory effect among other mechanisms. Is also used in other chronic pain conditions as well as emerging evidence it may be helpful for depression (low dose). No control group in study cited.
https://www.ncbi.nlm.nih.gov/pmc/art...__ffn_sectitle
My mom told me that when she entered the military after getting a battery of shots they all were given a scrub brush for each hand. Then all the girls spent the next few hours scrubbing the floor of the mess hall. I was planning to get vaxed after golf tomorrow but maybe I should get the shot first?
Cdc released updated vaccine effectiveness data yesterday re: hospitalization for the single variant mRNA vax+booster: https://www.cdc.gov/mmwr/volumes/71/wr/mm7142a3.htm
“Three-dose monovalent mRNA VE estimates against COVID-19–associated hospitalization decreased with time since vaccination. Three-dose VE during the BA.1/BA.2 and BA.4/BA.5 periods was 79% and 60%, respectively, during the initial 120 days after the third dose and decreased to 41% and 29%, respectively, after 120 days from vaccination.”
For those on the board in the know, is the initial effectiveness due to antibody response/prevalence and the loss of effectiveness because the t and B cells weren’t doing their thing?
I guess we’ll be finding out in several months if this bivalent version performs similarly….
There's probably also a statistical contribution. From the discussion portion:
"Although the analysis was stratified by time since last vaccination during each lineage predominance period, the median interval between receipt of the third dose and illness onset during the BA.4/BA.5 period in this analysis was 233 days compared with 145 days during the BA.1/BA.2 period; thus, the BA.4/BA.5 period disproportionately included patients further removed from vaccination, which likely contributed to the lower VE during this period....
The findings in this report are subject to at least four limitations. First, sample size was insufficient to assess VE varying over time for the BA.2 period separately, resulting in use of a combined BA.1/BA.2 group instead, or to demonstrate substantial waning during the BA.4/BA.5 period. Second, because lineage periods were pooled, the unique contributions of immune evasion associated with each lineage to VE could not be ascertained. Third, because previous infection could not be measured, its effect on VE estimates could only be inferred, not quantified. Finally, follow-up time after the fourth dose to assess waning immunity associated with this dose was insufficient."
Stratifying into only two groups necessarily ignores the continued increase in immunity in the unvaccinated members of each group with time outside of that qualitative split. The fact that the mean time between vaccination and disease increased so dramatically is probably owed in part to that. But add that there is still the problem of vaccinations being self-selecting, so there's likely a correlation between vaccinated and at-risk leading to comparatively more hospitalizations due to that higher risk (which existed independent of vaccination). Meaning, in this case, the last booster came sooner (longer ago)--in part because higher risk patients on average probably got them earlier. The onset interval went up by 88 days between the two periods, the first of which was barely over 2x that long. Average age rose, too.
It's just a shame they couldn't get large enough samples to further stratify either of the time intervals used. Hopefully the data on bivalent boosters is larger.
First a couple more answers are needed. One - they are reporting effectiveness against hospitalization. Two - they are comparing effectiveness to the unvaccinated. Most of the unvaccinated have some protection due to prior infection(s) at this time. That means today's VE is measuring something different than the original EUA studies reporting VE in the 90s.
From the CDC link: "Further, infections with earlier Omicron lineages, including BA.1 and BA.2, reduce vaccine effectiveness (VE) estimates because certain persons in the referent unvaccinated group have protection from infection-induced immunity."
IIRC, the booster came out during the delta surge, so some of the apparent loss in VE is due to the unvaccinated gaining immunity via sickness. You got boosted, they got sick. Both gained roughly equivalent immunity.
I suggest that the vaccine performs well. Probably a more interesting question is how three dose performed vs a 2 dose population. Or 4 dose vs 3. Or 5 vs 4. Since the readers of this thread are presumably considering whether to get another shot. (Or laughing at all us fools volunteering for the 5G government mind-control chip). The third dose is supposedly important in developing the longterm immunity. It's less clear to me that further boosters provide as much benefit (though this could be due to me not reading enough Covid studies - I decided the national health agencies are doing their job, and I generally follow their advice)
My take on getting a booster is it ought to cause both a temporary effect via increased antibody protection, and a longer lasting incremental effect due to further development of t and B cells. Several of the experts I follow have decided not to get 2nd or 3rd booster as they feel the evidence isn't strong enough. I think they're being pedantic but that's my opinion.
I'm not one of the real experts, though read a lot and try to synthesize and report accurately