Alors, i don't blame you^^ cuz even the real french will avoid the Canadiens and if spoken to by a Quebecios
they will reply in hinglish
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Wifey is getting the vaccine next week. I'll report in here and let the Nancy's know how it went.
Yo, Bub.....you know goddam good and well that you can't be talking that much shit without giving a whole lot of thoughts and prayers to the good lord jeezuz, honoring his martyrdom for the freedom fighters here to kill antifa in the name of god and wall street. He kicked the money traders out of the temple to make room for armed militias and did a gofundme in god's name. Got like three million hits day one. He gave three hundred bucks to the militias and went golfing after saying, 'You're on your own." Fuck yaah.
Pfizer approved. Release the hounds!!
PG ... that’s propaganda. Choose your sources better.
Not quite yet probably.......I am sure there is some more red tape to further delay the actual delivery of the vaccine into arms...
It “is” the weekend and those old bastards need to rest up. They seem to like the drama of playing it out to get the public outrage of “what’s taking them so long”...(which I believe they have achieved already)
God forbid a meeting on the weekend....or a Monday....or any weekday before noon.
As a healthy 20-something year old I’m at the back of line, so I won’t be able to get a jab til late next year probably.
Out of curiosity, something I haven’t seen discussed here is the possibility of long-term auto-immune side effects from an mRNA vaccine. The whole point (as I understand it) is that mRNA vaccines in some ways act like a virus itself, by hijacking the bodies cells to make proteins that look like the virus, but aren’t, to stimulate an immune response and create antibodies that will recognize the virus, which looks like the proteins the vaccine helped create.
What happens if that keeps going on (or messes with cell reproduction in unexpected ways)? Maybe not true but I feel like I recall reading something about part of the reason why COVID is a bitch is because various parts of the virus have a lot similarities to human proteins. Which would lend even more concern to auto immune questions, or the body becoming confused about what proteins/cells are and aren’t intruders.
Saying that the vaccine is “safe and effective” because there are no serious side effects 6 months later doesn’t really mean anything. If you injected 30,000 healthy people with the HIV virus, you wouldn’t have serious side effects in anyone for 5-10 years, let along 6 months. Does that mean HIV is safe? No. Lots of auto immune disorders are incredibly slow. And we really don’t understand what causes many of them. People with MS likely “have it” long before they actually become aware of what’s happening. We don’t know what causes that, what causes ALS, what causes most auto immune conditions.
As others mentioned, no mRNA vaccine has ever gotten out of animal trials. We have safety profiles for traditional vaccines, and with those we basically know that if you don’t see any issues right away, the vaccine is likely safe, because we have decades long safety profiles and thoroughly understand them and how they effect the body. There are hardly short term safety profiles for mRNA vaccines (creating them as we speak), let alone medium term or long term safety profiles for mRNA vaccines.
Personally, I may consider waiting for a traditional vaccine technology option for COVID. I’d have 0 qualms about taking one. The Astrozenica one (not mRNA, but still new tech) also seems (on the surface) like it may have less possibility of long term unintended side effects. mRNA vaccines are an unknown, and there is no way around that. That doesn’t mean that they are dangerous, or will cause any long term problems in any way, but I’d be curious if anyone can explain, or has a scientific study/paper that can explain why there isn’t a risk of long term problems? Because if there are long term side effects that show up in 2-10 years, the world is completely and totally fucked. Imagine if 70% of the population gets a chronic auto immune condition. It’ll make 2020 look like a rough first day of preschool.
There’s a reason the FDA usually takes agonizingly long to approve any medical procedure, drug, treatment, vaccine, etc. Even when it’s extremely clear that it’s safe/effective/not that complicated how it works.
I may be totally off base, perhaps because mRNA is so fragile, and not DNA, it gets worked out of the system shortly after it causes the cells to create the antibodies? And there is no possibility of lingering affects on cellular reproduction?
I’m certainly not an anti-vaxxer, I got my flu shot yesterday. Not because I’m concerned if o catch the flu, but because I understand that vaccinating everyone, even those not at risk, provides protection for the vulnerable and makes the entire population healthier. I understand they are clearly extremely beneficial and important to society. And I’’m planning on getting a COVID jab. Maybe not an mRNA one though. I would like to have some reasonable scientific assurance that the above concerns aren’t valid before I’d take an mRNA one.
And I’m not talking about the current societal impetus/need for a vaccine now because of the current death toll, economic problems, etc. I understand it. I have plenty of friends and extended family who work in hospitals. I’m aware of the COVID hell that’s going on. But I question whether this current hell, where mostly people over the average life expectancy are the ones dying (not that that is okay), would be better than risking the entire population’s health with something that we don’t really know how it will affect us long term? Maybe there isn’t a risk. I don’t know. It seems that using the mRNA vaccines for the elderly and high-risk people now, makes a ton of sense, because the virus is a much bigger threat to them and they don’t really have nearly the same concern of whether the vaccine could cause problems 5-10 years from now. Doing so will relieve a huge majority of the burden off the health care system and ICU units, and allow them to cope with fringe cases in the non-at risk population. And give time with masks and social distancing to A) develop traditional vaccines and/or B) create a longer safety profile for mRNA vaccines before giving it to every single person... Beyond that, I don’t know if society is being hasty...
https://www.google.com/amp/s/mobile..../idUKKBN27E0GD
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I believe in getting immunity the old-fashioned way: By letting a bat virus take control of my lungs and turn my face into a disgusting plague fountain while my immune system desperately Googles 'how to make spike protein antibodies'
Muggydude--according to this https://www.nytimes.com/2020/12/10/o...us-relief.html the mRNA makes one copy of the spike protein and is then destroyed. Unlike DNA, mRNA is not self replicating. Once each molecule mRNA in the 2 doses has produced one molecule of spike protein, no more protein is produced to elicit an ongoing immune reaction. Unlike a live virus infection like HIV infection, no part of the vaccine induced immune process is replicating--unless and until the subject is exposed to live coronavirus, in which case the immune reaction kicks and my producing more antibody and killer T cells.
All vaccines and natural infections produce an immune response. Your concern is that vaccination could produce an autoimmune response, and there is some evidence that it can https://www.ncbi.nlm.nih.gov/pmc/art...%E2%80%9397%5D
but keep in mind that natural infection can do the same thing--because it produces the same immune response as vaccination.
Waiting for a "traditional" vaccine would not protect you from an autoimmune reaction. The swine flu vaccine caused Guillain Barre Syndrome in 1/100,000 recipients. Influenza itself can cause GBS.
There is no guarantee that there will be a "traditional" vaccine. The Sanofi-GSK recombinant protein vaccine--which uses a technology currently used in some flu vaccines--is delayed due to lack of an immune response in older people. The vaccine is being reformulated to increase the antigen dose, but by the time it is ready for phase 3 trials it may be difficult to recruit volunteers when a proven vaccine is already available. The same problem confronts any vaccine that is not already in Phase 3.
If you aren't vaccinated the odds are very high that you will be infected with SARS-CoV-2 with the risk of death, permanent disability, or the induction of an autoimmune disease.
Relieved to see my high risk MIL who is in an assisted living home will be getting the V soon.
After spending most of the last year taking care of many, many incredibly acutely ill Covid-19 patients in my ICU, many of whom are now dead?
Fuck yeah I'm getting it. Most of my fellow RNs and the techs, and pretty much all the Docs say the same.